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NCT03899987 · ClinicalTrials.gov registry record · Phase 2

Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery

A Phase 2 study of Prostate Adenocarcinoma and Stage III Prostate Cancer AJCC v8, sponsored by Roswell Park Cancer Institute.

Active
Registry status
Phase 2
Development phase
12
Enrollment target
1
Study location

NCT03899987 is a Phase 2 study of Prostate Adenocarcinoma and Stage III Prostate Cancer AJCC v8 that is active but no longer recruiting, run by Roswell Park Cancer Institute. The registered enrollment target is 12 participants, below the 218-participant average among 99 other Prostate Adenocarcinoma trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03899987, a Phase 2 study of Prostate Adenocarcinoma and Stage III Prostate Cancer AJCC v8, is active but no longer recruiting, sponsored by Roswell Park Cancer Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

This phase II trial studies how well enteric-coated (EC) aspirin and rintatolimod with or without interferon-alpha 2b work in treating patients with prostate cancer before surgery. EC Aspirin may help to keep the prostate cancer from coming back. Rintatolimod may stimulate the immune system and interfere with the ability of tumor cells to grow and spread. Interferon-alpha 2b may improve the body's natural response to infections and may slow tumor growth. It is not yet known how well rintatolimod, EC aspirin, and interferon-alpha 2b work in treating patients with prostate cancer undergoing surgery.

Interventions

  • PROCEDURE Radical Prostatectomy
  • BIOLOGICAL Recombinant Interferon Alfa-2b
  • DRUG EC Aspirin
  • DRUG Rintatolimod

Study Locations (1)

New York

  • Roswell Park Cancer Institute - Buffalo

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2019-11-29
Est. Completion 2026-11-29
Phase Phase 2

Sponsor

Roswell Park Cancer Institute

365 total trials

What the Registry Record Tells You About NCT03899987

The ClinicalTrials.gov registry entry for NCT03899987 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 218-participant average among 99 other Prostate Adenocarcinoma trials with a reported enrollment target (94% lower). The listed sponsor is Roswell Park Cancer Institute, which has 365 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Prostate Adenocarcinoma appearing as the primary indexed condition, and to 4 interventions - of which Radical Prostatectomy is the first listed.

NCT03899987 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT03899987 about?

NCT03899987 is a clinical study titled "Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery". This phase II trial studies how well enteric-coated (EC) aspirin and rintatolimod with or without interferon-alpha 2b work in treating patients with prostate cancer before surgery. EC Aspirin may help to keep the prostate cancer from coming back. Rintatolimod may stimulate the immune system and inte...

What is the current status of trial NCT03899987?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2019-11-29. Estimated completion is 2026-11-29.

What conditions does trial NCT03899987 study?

This clinical trial studies the following conditions: Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage I Prostate Cancer AJCC v8, Stage IIC Prostate Cancer AJCC v8.

What interventions are being tested in trial NCT03899987?

The interventions under investigation include: Radical Prostatectomy (PROCEDURE), Recombinant Interferon Alfa-2b (BIOLOGICAL), EC Aspirin (DRUG), Rintatolimod (DRUG).

Who is sponsoring clinical trial NCT03899987?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03899987 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.