Roswell Park Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Roswell Park Cancer Institute sits in the top decile of US sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count).

365 total trials 57 currently recruiting 200 completed early-phase tilt top decile by trial count

Roswell Park Cancer Institute: 365 sponsored US clinical trials, 57 recruiting.

Roswell Park Cancer Institute sponsors 365 registered US clinical trials on ClinicalTrials.gov, 57 of them currently recruiting, and 200 completed. 7 of these trials are in Phase 3-4 (later-stage) and 238 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Leukemia, with 9 trials.

Top-decile sponsor footprint

Roswell Park Cancer Institute ranks in the top decile of sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 18/100

200 of 279 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (71.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

365 total, page 3 of 8

COMPLETED Early Phase 1

A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence

NCT04298606

COMPLETED NA

Yoga Intervention for the Improvement of Cancer-Related Stress in Cancer Survivors

NCT04754529

COMPLETED NA

Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]

NCT05030194

COMPLETED NA

Weight Loss Interventions for Black Adults of Faith

NCT04557540

COMPLETED Phase 1

Behavioral Dietary Intervention for the Improvement of Bladder Cancer Survivorship

NCT04548193

COMPLETED

Nicotine Vapor Specific Sensory Measurement

NCT04533542

COMPLETED NA

Effects of Filter Ventilation and Ventilation Information on Product Use Behaviors in Cigarette Smokers

NCT04744285

COMPLETED NA

Awareness, Information, and Resources for Lung Cancer Screening Program for Community-Partnered Lung Cancer Screening

NCT04635761

TERMINATED Phase 1

Rintatolimod and IFN Alpha-2b for the Treatment of COVID-19 in Cancer Patients

NCT04379518

COMPLETED Phase 1

Talazoparib and Gemtuzumab Ozogamicin for the Treatment of CD33 Positive Relapsed or Refractory Acute Myeloid Leukemia

NCT04207190

COMPLETED Phase 4

Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

NCT04502095

COMPLETED NA

Fermented Milk Supplementation on Symptoms of Disease and Treatment in Patients With Multiple Myeloma

NCT04530812

COMPLETED NA

Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study

NCT04231539

COMPLETED Phase 1

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

NCT03735095

TERMINATED NA

Episodic Future Thinking and Future Thinking Priming for Smoking Cessation

NCT04297332

COMPLETED Phase 2

TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study

NCT04109924

COMPLETED Phase 2

Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma

NCT04097028

COMPLETED Phase 2

Denosumab in Treating Patients With Bone Loss Due to Donor Stem Cell Transplant

NCT03925532

COMPLETED NA

Strength Training in Improving Pain and Quality of Life in Patients With Multiple Myeloma

NCT03793907

COMPLETED Phase 1

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

NCT04081389

TERMINATED NA

Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer

NCT04110249

COMPLETED Phase 1

Health Service Intervention for the Improvement of Access and Adherence to Colorectal Cancer Screening

NCT04607291

COMPLETED Phase 1

Enzalutamide With Venetoclax in Treating Patients With Metastatic Castration Resistant Prostate Cancer

NCT03751436

TERMINATED Phase 1

Porfimer Sodium Interstitial Photodynamic Therapy With or Without Standard of Care Chemotherapy in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer

NCT03727061

TERMINATED Phase 1

CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma

NCT03727789

TERMINATED NA

Experimental Tobacco Marketplace in Regulating Flavored Tobacco Products in Menthol Cigarette Smokers

NCT03897530

TERMINATED Phase 2

Palliative Management of Inoperable Malignant Bowel Obstruction

NCT04027348

COMPLETED Phase 1

Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

NCT03879694

TERMINATED Phase 2

Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic Origin

NCT03736720

COMPLETED

Effects of Filter Ventilation on Sensory Response, Smoking Topography, and Inhalation in Current Every Day Cigarette Smokers

NCT04060446

TERMINATED NA

Impact of Early Mobility on Post-Surgery Recovery in Patients Undergoing Oncologic Surgeries

NCT04000581

TERMINATED NA

Exercise and Nutrition Education in Improving Physical Function and Quality of Life in Older Breast Cancer Survivors

NCT03751449

TERMINATED Phase 1

Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT03691376

COMPLETED NA

Breast Cancer Pathways Program Impact on Patient Shared Decision Making and Experience in Academic and Community Practice

NCT04297384

COMPLETED NA

A Home-Based Walking Program and rTMS in Helping Breast Cancer Survivors Get More Physical Activity

NCT03789877

COMPLETED Early Phase 1

Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer

NCT03599453

COMPLETED NA

Parenting Skills Intervention in Improving Medication Adherence in Pediatric Cancer Patients

NCT03895918

COMPLETED NA

Problem Solving Skills Training in Adult Cancer Survivors: Bright IDEAS-AC

NCT03567850

TERMINATED Phase 2

Abatacept, Ixazomib Citrate, and Dexamethasone in Treating Patients With Multiple Myeloma Resistant to Chemotherapy

NCT03457142

TERMINATED NA

Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers

NCT03630601

COMPLETED Phase 2

Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy

NCT03574792

COMPLETED Phase 2

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

NCT03403634

COMPLETED Phase 1

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

NCT03358719

TERMINATED Phase 2

Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer

NCT03090412

COMPLETED NA

Mindfulness-Based Stress Reduction in Helping Participants With Metastatic Breast Cancer

NCT03683147

COMPLETED Phase 1

Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer

NCT03211416

TERMINATED Phase 2

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

NCT03333486

COMPLETED Early Phase 1

Intravital Microscopy in Evaluating Patients With Primary Peritoneal, Fallopian Tube, or Stage IA-IV Ovarian Cancer

NCT03297489

COMPLETED Early Phase 1

Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteers

NCT04484532

COMPLETED NA

Exercise in Improving Health and Quality of Life in Breast Cancer Survivors

NCT03679559

← Previous Page 3 of 8 Next →

What is open in the Roswell Park Cancer Institute pipeline

57 recruiting of 365 indexed (16% open); 200 completed (55%).

Phase mix: 7 late (III/IV) vs 238 early (I/II) (early-phase heavy).

Top condition: Leukemia (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Roswell Park Cancer Institute: open-pipeline peers nationwide

Peers matched on 365 registered trials and 16% open enrollment, not the therapeutic-area sidebar.

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share Roswell Park Cancer InstituteUNC Lineberger Comprehensive Cancer CenterNew York State Psychiatric InstituteUniversity of California, IrvineNorthwell HealthCambridge Health AllianceLouisiana State University Health Sciences Center in New OrleansUniversity of Southern CaliforniaIncyte Corporation
Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 365 trials (± recruiting share)

Sponsors near 16% open enrollment (± trial volume)

What to do with this Roswell Park Cancer Institute page

365 registered trials is a research-attention snapshot, not an endorsement of Roswell Park Cancer Institute or any single study.

  • 57 of Roswell Park Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Leukemia is the condition Roswell Park Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Leukemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Roswell Park Cancer Institute pipeline card: 365 registered trials from official public datasets.Report a data error.