Radiation Therapy Oncology Group

144 total trials 131 completed

Radiation Therapy Oncology Group sponsors 144 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 131 completed. 55 of these trials are in Phase 3-4 (later-stage) and 82 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 10 trials.

Trial Pipeline

144 total, page 2 of 3

COMPLETED Phase 3

Radiation Therapy in Treating Patients With Stage II Prostate Cancer

NCT00331773

COMPLETED Phase 2

Intensity-Modulated Radiation Therapy to the Pelvis With or Without Chemotherapy in Treating Patients With Endometrial Cancer or Cervical Cancer That Has Been Removed By Surgery

NCT00331760

COMPLETED Phase 3

Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

NCT00329797

COMPLETED NA

Positron Emission Tomography Scan and CT Scan in Planning Radiation Therapy for Patients With Stage II or Stage III Non-Small Cell Lung Cancer

NCT00310219

COMPLETED Phase 3

Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

NCT00304031

COMPLETED Phase 3

Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer

NCT00288080

COMPLETED Phase 1

Radiation Therapy in Treating Patients With Liver Metastases

NCT00255814

COMPLETED Phase 3

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck Cancer

NCT00265941

COMPLETED

Collecting and Storing Tissue Samples From Patients With Head and Neck Cancer

NCT00898300

TERMINATED Phase 3

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery

NCT00113399

TERMINATED Phase 3

Cisplatin and Docetaxel With or Without Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Newly Diagnosed Stage III Non-Small Cell Lung Cancer

NCT00113386

COMPLETED Phase 2

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

NCT00114140

COMPLETED Phase 2

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT00099125

COMPLETED Phase 2

Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage III Non-Small Cell Lung Cancer

NCT00096226

COMPLETED Phase 2

Radiation Therapy in Treating Patients With Stage II or Stage III Prostate Cancer

NCT00091390

COMPLETED Phase 2

Stereotactic Body Radiation Therapy in Treating Patients With Inoperable Stage I or Stage II Non-Small Cell Lung Cancer

NCT00087438

COMPLETED Phase 2

Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Treating Patients With Resected Stage III or Stage IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck

NCT00084318

COMPLETED Phase 2

Cetuximab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Unresectable Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer

NCT00081302

COMPLETED Phase 2

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

NCT00081289

COMPLETED Phase 3

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

NCT00075868

COMPLETED Phase 2

Combination Chemotherapy Followed By Chemoradiotherapy, With or Without Surgery, in Treating Patients With Resectable Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

NCT00069953

COMPLETED Phase 2

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

NCT00068237

COMPLETED Phase 1

3-Dimensional Conformal Radiation Therapy In Treating Women With Stage I or Stage II Breast Cancer Previously Treated With Lumpectomy and Axillary Node Dissection

NCT00068263

COMPLETED Phase 1

Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

NCT00068250

COMPLETED Phase 3

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer

NCT00063882

COMPLETED Phase 2

Cisplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

NCT00066222

TERMINATED Phase 2

Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without Chemotherapy

NCT00077064

COMPLETED Phase 1

Chemotherapy Combined With Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

NCT00059761

COMPLETED Phase 2

Brain Irradiation in Treating Patients With Limited-Stage Small Cell Lung Cancer

NCT00057746

COMPLETED Phase 2

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

NCT00057785

COMPLETED NA

Sildenafil in Treating Erectile Dysfunction in Patients With Prostate Cancer

NCT00057759

COMPLETED Phase 3

Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer

NCT00053053

COMPLETED Phase 2

Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer

NCT00055601

COMPLETED Phase 3

Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate Cancer

NCT00030654

COMPLETED Phase 3

Radiation Therapy in Preventing Central Nervous System (CNS) Metastases in Patients With Non-Small Cell Lung Cancer

NCT00048997

COMPLETED Phase 3

Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Head and Neck Cancer

NCT00047008

COMPLETED Phase 1

Celecoxib and Radiation Therapy in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer

NCT00046839

COMPLETED Phase 2

Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas

NCT00033280

COMPLETED Phase 2

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

NCT00031967

COMPLETED Phase 3

Radiation Therapy in Treating Patients With Stage II Prostate Cancer

NCT00033631

COMPLETED Phase 1

Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma

NCT00023725

COMPLETED Phase 1

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

NCT00012012

COMPLETED Phase 1

Radiation Therapy Plus Celecoxib, Fluorouracil, and Cisplatin in Patients With Locally Advanced Cervical Cancer

NCT00023660

COMPLETED Phase 1

Chemotherapy, SU5416, Radiation Therapy, and Surgery in Treating Patients With Soft Tissue Sarcoma

NCT00023738

COMPLETED Phase 1

Radiation Therapy Combined With Paclitaxel and Carboplatin in Treating Patients With Stage III Non-Small Cell Lung Cancer

NCT00023673

TERMINATED Phase 2

Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

NCT00006916

COMPLETED Phase 1

Gemcitabine, Carboplatin or Paclitaxel Plus Radiation Therapy in Treating Patients With Stage IIIA or IIIB Non-Small Cell Lung Cancer

NCT00016315

COMPLETED Phase 2

Chemotherapy and Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Stomach Who Have Undergone Surgery

NCT00011960

COMPLETED Phase 2

Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach

NCT00009880

COMPLETED Phase 2

Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer

NCT00011999

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What the Pipeline for Radiation Therapy Oncology Group Shows

According to the ClinicalTrials.gov registry, Radiation Therapy Oncology Group is linked to 144 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 131 are already marked complete, representing roughly 91% of the total.

The phase mix for Radiation Therapy Oncology Group reports 55 late-stage studies (Phase 3 and Phase 4 combined) and 82 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Radiation Therapy Oncology Group is Prostate Cancer with 10 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.