Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00091390 · ClinicalTrials.gov registry record · Phase 2

Radiation Therapy in Treating Patients With Stage II or Stage III Prostate Cancer

A Phase 2 study, sponsored by Radiation Therapy Oncology Group.

Completed
Registry status
Phase 2
Development phase
129
Enrollment target

NCT00091390: Completed Phase 2 study, sponsored by Radiation Therapy Oncology Group.

NCT00091390 is a Phase 2 study that has completed, run by Radiation Therapy Oncology Group. The registered enrollment target is 129 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00091390, a Phase 2 study, has completed, sponsored by Radiation Therapy Oncology Group.

COMPLETED
Registry status
Phase 2
Development phase
129 participants
Enrollment target

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Internal radiation therapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving internal radiation therapy together with external-beam radiation therapy works in treating patients with stage II or stage III prostate cancer.

Primary Outcome

Adverse events (AE) were graded using the Common Terminology Criteria for Adverse Events (CTCAE) v3.0. Grade refers to the severity of the AE. The CTCAE v3.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild, Grade 2 Moderate, Grade 3 Severe, Grade 4 Life-threatening or disabling, Grade 5 Death related to AE. "Late" is defined as occurring after 9 months from the start of study treatment. Because of the lead time of

Interventions

  • RADIATION External beam radiotherapy
  • RADIATION High Dose brachytherapy boost

Trial Details

FieldValue
Enrollment Target 129 participants
Start Date 2004-07
Est. Completion 2016-12
Phase Phase 2
Radiation Therapy Oncology Group

144 total trials

What the finished NCT00091390 record still lists

NCT00091390 is an interventional study that assigns participants to a tested intervention. The registered 129 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.

The record links to 0 conditions, and to 2 interventions - of which External beam radiotherapy is the first listed.

NCT00091390 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00091390 about?

NCT00091390 is a clinical study titled "Radiation Therapy in Treating Patients With Stage II or Stage III Prostate Cancer". RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Internal radiation therapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells. PURPOSE: This phase II t...

What is the current status of trial NCT00091390?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 129 participants. The study started on 2004-07. Estimated completion is 2016-12.

What interventions are being tested in trial NCT00091390?

The interventions under investigation include: External beam radiotherapy (RADIATION), High Dose brachytherapy boost (RADIATION).

Who is sponsoring clinical trial NCT00091390?

This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00091390's enrollment target sits among peer trials

129 553rd of 2000 higher than 1,448 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03619850 · 129 participants · Phase 3

    A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)

  • NCT05704361 · 129 participants · Phase 1

    A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis

  • NCT05919849 · 129 participants · Phase 1

    Supporting Parents in Affirming Their Children's Experiences of Stigma

  • NCT06313749 · 129 participants · NA

    Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00091390, the US trial registry maintained by the National Library of Medicine. NCT00091390 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.