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NCT00033280 · ClinicalTrials.gov registry record · Phase 2

Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas

A Phase 2 study, sponsored by Radiation Therapy Oncology Group.

Completed
Registry status
Phase 2
Development phase
42
Enrollment target

NCT00033280: Completed Phase 2 study, sponsored by Radiation Therapy Oncology Group.

NCT00033280 is a Phase 2 study that has completed, run by Radiation Therapy Oncology Group. The registered enrollment target is 42 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00033280, a Phase 2 study, has completed, sponsored by Radiation Therapy Oncology Group.

COMPLETED
Registry status
Phase 2
Development phase
42 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining temozolomide with radiation therapy in treating patients who have newly diagnosed anaplastic oligodendrogliomas or mixed anaplastic oligoastrocytomas.

Interventions

  • DRUG temozolomide
  • RADIATION radiation therapy
  • PROCEDURE neoadjuvant therapy

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2002-07
Est. Completion 2018-05-14
Phase Phase 2
Radiation Therapy Oncology Group

144 total trials

What the finished NCT00033280 record still lists

NCT00033280 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower).

The record links to 0 conditions, and to 3 interventions - of which temozolomide is the first listed.

NCT00033280 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00033280 about?

NCT00033280 is a clinical study titled "Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effec...

What is the current status of trial NCT00033280?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2002-07. Estimated completion is 2018-05-14.

What interventions are being tested in trial NCT00033280?

The interventions under investigation include: temozolomide (DRUG), radiation therapy (RADIATION), neoadjuvant therapy (PROCEDURE).

Who is sponsoring clinical trial NCT00033280?

This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00033280's enrollment target sits among peer trials

42 1339th of 2000 higher than 649 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00033280, the US trial registry maintained by the National Library of Medicine. NCT00033280 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.