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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Radiation Toxicity: early-phase trial registry

3 of 14 indexed Radiation Toxicity trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,230 of 28,707 conditions by registered trial count.

14 US clinical trials · 3 currently recruiting · #1,230 of 28,707 conditions by registered trial count

Radiation Toxicity: 14 US clinical trials tracked, 3 recruiting.

Radiation Toxicity is the subject of 14 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Radiation Therapy Oncology Group, running 2 of these trials.

Enrollment posture brief

Registry condition radiation-toxicity

OPEN 3 | RECR 21% | LATE 1 | EARLY 6 | RANK #1230 | SPON 2

Nearest open-share peer: Cervical Adenocarcinoma (21% recruiting · 14 trials)

Acute Respiratory Failure35.7%Adherence, Medication35.7%Acromegaly28.6%Radiation Toxicity (this)21%Abscess7.1%
Open-enrollment share among volume-matched conditions near Radiation Toxicity

Radiation Toxicity lists 3 open slots (21% of 14 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Radiation Toxicity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Radiation Toxicity is recruiting below its size-band peers.

    3 of 14 indexed trials (21.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Radiation Toxicity trials is spread across many organizations.

    Radiation Therapy Oncology Group accounts for 2 of 14 trials (14.3%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Radiation Toxicity enrolment sits around 76 participants.

    Median target enrolment is 76 among the 13 trials that report a genuine target (sentinel values excluded). 7 of those (53.8%) plan for fewer than 100 participants.

  4. Radiation Toxicity splits between interventional and observational designs.

    9 interventional and 5 observational studies make up this index (64.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 21Phase 31

Open and recent trials

14 total, page 1 of 1

RECRUITING Phase 1 122 participants

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

UNC Lineberger Comprehensive Cancer Center

NCT04700527

RECRUITING Early Phase 1 30 participants

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

University of Rochester

NCT05530655

RECRUITING NA 20 participants

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Indiana University

NCT06059586

ACTIVE NOT RECRUITING 3,561 participants

Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer

University of California, San Francisco

NCT00769223

ACTIVE NOT RECRUITING 273 participants

Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy

Ohio State University Comprehensive Cancer Center

NCT02259218

ACTIVE NOT RECRUITING 221 participants

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy

Abramson Cancer Center at Penn Medicine

NCT04305613

COMPLETED 1,000 participants

Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer

Wake Forest University Health Sciences

NCT01407770

COMPLETED Phase 3 176 participants

Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ

North Central Cancer Treatment Group

NCT00438659

COMPLETED 76 participants

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Case Comprehensive Cancer Center

NCT00255671

COMPLETED Phase 1 73 participants

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

Alliance for Clinical Trials in Oncology

NCT00006012

COMPLETED NA 59 participants

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Radiation Therapy Oncology Group

NCT00007007

COMPLETED Phase 1 45 participants

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

Radiation Therapy Oncology Group

NCT00012012

COMPLETED Phase 2 25 participants

Radiation Therapy Plus Amifostine in Treating Patients With Primary Prostate Cancer

University of Arizona

NCT00003307

COMPLETED Phase 1

Monoclonal Antibody Therapy in Treating Patients With Leukemia

National Cancer Institute (NCI)

NCT00019227

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 1
Phase 3 1

Named interventions

Most-linked intervention names on Radiation Toxicity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

amifostine trihydrate Drug
2 trials
radiation therapy Radiation
2 trials
quality-of-life assessment Procedure
2 trials
laboratory biomarker analysis Other
2 trials
yttrium Y 90 daclizumab Radiation
1 trials
pentetic acid calcium Drug
1 trials
mometasone furoate Drug
1 trials
Intracavitary brachytherapy Radiation
1 trials

US sites by state

Facility locations filed on Radiation Toxicity trials. A trial with sites in several states counts in each.

Ohio 3 trials
Arizona 3 trials
Pennsylvania 2 trials
New York 2 trials
New Jersey 2 trials
North Carolina 2 trials
Illinois 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Radiation Toxicity page

14 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Radiation Toxicity condition card totals 14 registered trials; most-linked intervention amifostine trihydrate; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.