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ACTIVE NOT RECRUITING Phase 3

Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer

NCT00567580 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as flutamide, bicalutamide, and luteinizing hormone-releasing hormone agonist, may lessen the amount of androgens made by the body. It is not yet known which regimen of radiation therapy with or without androgen-deprivation therapy is more effective for prostate cancer. PURPOSE: This randomized phase III trial is studying prostate radiation therapy to see how well it works compared with short-term androgen deprivation therapy given together with pelvic lymph node radiation therapy with or without prostate radiation therapy in treating patients with a rising PSA after surgery for prostate cancer.

Conditions Studied

Interventions

  • DRUG LHRH agonist
  • RADIATION PBRT
  • RADIATION PLNRT
  • DRUG AA

Study Locations (20)

California

  • Auburn Radiation Oncology — Auburn
  • Peninsula Medical Center — Burlingame
  • Radiation Oncology Centers - Cameron Park — Cameron Park
  • Mercy Cancer Center at Mercy San Juan Medical Center — Carmichael
  • East Bay Radiation Oncology Center — Castro Valley
  • Valley Medical Oncology Consultants - Castro Valley — Castro Valley
  • Enloe Cancer Center at Enloe Medical Center — Chico
  • Valley Medical Oncology — Fremont
  • Washington Township Hospital — Fremont
  • California Cancer Center - Woodward Park Office — Fresno
  • Cancer Care Associates — Fresno
  • Rebecca and John Moores UCSD Cancer Center — La Jolla
  • Veterans Affairs Medical Center - Long Beach — Long Beach
  • Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center — Los Angeles
  • USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles

Arizona

  • Arizona Center for Cancer Care - Peoria — Peoria
  • Arizona Oncology Services Foundation — Phoenix
  • Arizona Oncology - Tucson — Tucson

Alabama

  • UAB Comprehensive Cancer Center — Birmingham

Alaska

  • Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital — Fairbanks

Trial Details

FieldValue
Enrollment Target 1,792 participants
Start Date 2008-02
Phase Phase 3

Sponsor

Radiation Therapy Oncology Group

37 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00567580

The ClinicalTrials.gov registry entry for NCT00567580 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,792 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Radiation Therapy Oncology Group, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 4 interventions — of which LHRH agonist is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00567580 reports 20 study locations spanning 4 distinct geographic areas — top geographies include California, Arizona, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00567580 about?

NCT00567580 is a clinical study titled "Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer". RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as flutamide, bicalutamide, and luteinizing hormone-releasing hormone agonist, may lessen the amount of androgens made by the body. It is not y...

What is the current status of trial NCT00567580?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,792 participants. The study started on 2008-02.

What conditions does trial NCT00567580 study?

This clinical trial studies the following conditions: Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00567580?

The interventions under investigation include: LHRH agonist (DRUG), PBRT (RADIATION), PLNRT (RADIATION), AA (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00567580?

This trial is sponsored by Radiation Therapy Oncology Group, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00567580 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial