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NCT00922974 · ClinicalTrials.gov registry record · Phase 2
Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis
A Phase 2 study, sponsored by Radiation Therapy Oncology Group.
- Completed
- Registry status
- Phase 2
- Development phase
- 399
- Enrollment target
NCT00922974: Completed Phase 2 study, sponsored by Radiation Therapy Oncology Group.
NCT00922974 is a Phase 2 study that has completed, run by Radiation Therapy Oncology Group. The registered enrollment target is 399 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (200% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00922974, a Phase 2 study, has completed, sponsored by Radiation Therapy Oncology Group.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 399 participants
- Enrollment target
Study Summary
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. PURPOSE: This randomized phase II/III trial is studying how well image-guided radiosurgery or stereotactic body radiation therapy works and compares it to external-beam radiation therapy in treating patients with localized spine metastasis.
Primary Outcome
Treatment delivery was centrally reviewed by the study chair and medical physics co-chair. Success was defined as having a review of "per protocol" or "minor variation". A 70% success rate was required for continuation to the phase III component. * Target volume compliance in is defined as the following levels of target coverage in reference to dose volume: * Per protocol: ≥ 90% * Minor variation: 80%-90% * Major deviation: \<80% of of dose volume. * Image-Guided Radiotherapy (IGRT) comp
Interventions
- RADIATION External beam radiation therapy
- RADIATION Radiosurgery/SBRT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 399 participants |
| Start Date | 2009-11 |
| Est. Completion | 2020-04-06 |
| Phase | Phase 2 |
What the finished NCT00922974 record still lists
NCT00922974 is an interventional study that assigns participants to a tested intervention. The registered 399 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (200% higher).
The record links to 0 conditions, and to 2 interventions - of which External beam radiation therapy is the first listed.
NCT00922974 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00922974 about?
NCT00922974 is a clinical study titled "Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis". RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. PURPOSE: This randomized phase II/III trial is studying how well image-guided radiosurgery or stereotactic body radiation therapy w...
What is the current status of trial NCT00922974?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 399 participants. The study started on 2009-11. Estimated completion is 2020-04-06.
What interventions are being tested in trial NCT00922974?
The interventions under investigation include: External beam radiation therapy (RADIATION), Radiosurgery/SBRT (RADIATION).
Who is sponsoring clinical trial NCT00922974?
This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00922974's enrollment target sits among peer trials
399 103rd of 2000 higher than 1,898 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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