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Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma
NCT00895622 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor, such as 3-dimensional conformal radiation therapy and intensity-modulated radiation therapy, may kill more tumor cells and cause less damage to normal tissue. It is not yet known whether observation is more effective than radiation therapy in treating patients with meningioma. PURPOSE: This phase II trial is studying observation to see how well it works compared with radiation therapy in treating patients with grade I, grade II, or grade III meningioma.
Conditions Studied
Interventions
- RADIATION 54 Gy radiotherapy
- RADIATION 60 Gy radiotherapy
Study Locations (20)
Arizona
- Arizona Oncology Services Foundation — Phoenix
- Mayo Clinic Hospital — Phoenix
- Mayo Clinic Scottsdale — Scottsdale
Georgia
- Emory Crawford Long Hospital — Atlanta
- Winship Cancer Institute of Emory University — Atlanta
- Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center — Savannah
Kansas
- Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City
- Kansas City Cancer Centers - Southwest — Overland Park
- CCOP - Kansas City — Prairie Village
California
- City of Hope Comprehensive Cancer Center — Duarte
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco
Florida
- University of Florida Shands Cancer Center — Gainesville
- Baptist-South Miami Regional Cancer Program — Miami
Connecticut
- Yale Cancer Center — New Haven
Idaho
- Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center — Boise
Illinois
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 244 participants |
| Start Date | 2009-06 |
| Est. Completion | 2023-08-15 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00895622
The ClinicalTrials.gov registry entry for NCT00895622 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 244 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Radiation Therapy Oncology Group, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 2 interventions — of which 54 Gy radiotherapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00895622 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Arizona, Georgia, Kansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00895622 about?
NCT00895622 is a clinical study titled "Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma". RATIONALE: Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor, such as 3-dimensional conformal radiation therapy and intensity-modulated radiation therap...
What is the current status of trial NCT00895622?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 244 participants. The study started on 2009-06. Estimated completion is 2023-08-15.
What conditions does trial NCT00895622 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00895622?
The interventions under investigation include: 54 Gy radiotherapy (RADIATION), 60 Gy radiotherapy (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00895622?
This trial is sponsored by Radiation Therapy Oncology Group, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00895622 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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