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NCT06630728 · ClinicalTrials.gov registry record · Phase 4
Addiction Potential of Very Low Nicotine Filtered Little Cigars
A Phase 4 study of Smoking (Tobacco) Addiction, sponsored by Ohio State University Comprehensive Cancer Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06630728: Recruiting Phase 4 study of Smoking (Tobacco) Addiction, sponsored by Ohio State University Comprehensive Cancer Center.
NCT06630728 is a Phase 4 study of Smoking (Tobacco) Addiction that is actively recruiting participants, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 50 participants, below the 387-participant average among 6 other Smoking (Tobacco) Addiction trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06630728, a Phase 4 study of Smoking (Tobacco) Addiction, is actively recruiting participants, sponsored by Ohio State University Comprehensive Cancer Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users. The main question\[s\] it aims to answer are: Are puffing behaviors, appeal/satisfaction, craving suppression, pharmacokinetic effects, and demand similar between the regular cigars smoked by participants, normal nicotine study cigars and very low nicotine study cigars? Are health effects and toxicant exposure similar between the regular cigars smoked by participants, normal nicotine study cigars and very low nicotine study cigars? Participants will attend three study visits at OSU. Each visit would last up to 4 hours. During visits, they will * fill several surveys * provide blood samples * perform breathing tests * complete smoking sessions using either their own cigars or the study cigars.
Primary Outcome
Derived from puff topography, total puff volume indicates the total amount of smoke inhaled during the smoking session. Units: mL
Conditions Studied
Interventions
- DRUG Reduced Nicotine Content Cigars
- DRUG Normal nicotine content cigar
- DRUG Usual brand cigar
Study Locations (1)
Ohio
- The Ohio State University - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-02-13 |
| Est. Completion | 2028-01 |
| Phase | Phase 4 |
What NCT06630728 shows while recruiting
NCT06630728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 387-participant average among 6 other Smoking (Tobacco) Addiction trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Smoking (Tobacco) Addiction appearing as the primary indexed condition, and to 3 interventions - of which Reduced Nicotine Content Cigars is the first listed.
NCT06630728 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06630728 about?
NCT06630728 is a clinical study titled "Addiction Potential of Very Low Nicotine Filtered Little Cigars". The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users. The main question\[s\] it aims to answer are: Are puffing behaviors, appeal/satisfaction, crav...
What is the current status of trial NCT06630728?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2025-02-13. Estimated completion is 2028-01.
What conditions does trial NCT06630728 study?
This clinical trial studies the following conditions: Smoking (Tobacco) Addiction.
What interventions are being tested in trial NCT06630728?
The interventions under investigation include: Reduced Nicotine Content Cigars (DRUG), Normal nicotine content cigar (DRUG), Usual brand cigar (DRUG).
Who is sponsoring clinical trial NCT06630728?
This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06630728 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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