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NCT07609030 · ClinicalTrials.gov registry record · NA

A Cognitive Training Intervention for Improving Cognitive and Neurological Outcomes in Patients Undergoing Treatment for Relapsed or Refractory Multiple Myeloma or B-cell Non-Hodgkin Lymphoma

A NA study, sponsored by Ohio State University Comprehensive Cancer Center.

Recruiting
Registry status
NA
Development phase
90
Enrollment target

NCT07609030: Recruiting NA study, sponsored by Ohio State University Comprehensive Cancer Center.

NCT07609030 is a NA study that is actively recruiting participants, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 90 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07609030, a NA study, is actively recruiting participants, sponsored by Ohio State University Comprehensive Cancer Center.

RECRUITING
Registry status
NA
Development phase
90 participants
Enrollment target

Study Summary

This clinical trial evaluates whether an online cognitive training intervention (Intervention to enhance Cognitive Augmentation and Neuroplasticity \[I-CAN\]), delivered before and after treatment with chimeric antigen receptor T-cell therapy, works to improve cognitive and neurological outcomes in patients with multiple myeloma or B-cell non-Hodgkin lymphoma that has come back after a period of improvement (relapsed) or does not respond to treatment (refractory). Cancer treatment can have significant short and long-term side effects, including cognitive and neurological side effects such as impairments in attention, memory, language, and executive function. The I-CAN program is a form of cognitive training. Cognitive training is a therapeutic approach designed to improve and restore cognitive functioning, based on the brain's ability to reorganize and form new neural connections to accomplish tasks. I-CAN provides five core elements necessary for training the brain to create new neural connections including speed of processing, accuracy of processing, adaptivity, generalizability, and engagement. The I-CAN intervention, when delivered before and after therapy, may help reduce the cognitive side effects of treatment in patients with relapsed or refractory multiple myeloma or B-cell non-Hodgkin lymphoma.

Primary Outcome

Descriptive statistics will be used to examine adherence, defined as the percent completion of I-CAN cognitive training before and after infusion.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Survey Administration
  • OTHER Electronic Health Record Review
  • OTHER Cognitive Intervention

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2026-04-28
Est. Completion 2027-12-31
Phase NA

What NCT07609030 shows while recruiting

NCT07609030 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 4 interventions - of which Biospecimen Collection is the first listed.

NCT07609030 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07609030 about?

NCT07609030 is a clinical study titled "A Cognitive Training Intervention for Improving Cognitive and Neurological Outcomes in Patients Undergoing Treatment for Relapsed or Refractory Multiple Myeloma or B-cell Non-Hodgkin Lymphoma". This clinical trial evaluates whether an online cognitive training intervention (Intervention to enhance Cognitive Augmentation and Neuroplasticity \[I-CAN\]), delivered before and after treatment with chimeric antigen receptor T-cell therapy, works to improve cognitive and neurological outcomes in ...

What is the current status of trial NCT07609030?

This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2026-04-28. Estimated completion is 2027-12-31.

What interventions are being tested in trial NCT07609030?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Electronic Health Record Review (OTHER), Cognitive Intervention (OTHER).

Who is sponsoring clinical trial NCT07609030?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07609030's enrollment target sits among peer trials

90 941st of 2000 higher than 1,029 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07609030, the US trial registry maintained by the National Library of Medicine. NCT07609030 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.