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NCT06260683 · ClinicalTrials.gov registry record · NA

A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior

A NA study of Cigarette Smoking-Related Carcinoma, sponsored by Ohio State University Comprehensive Cancer Center.

Recruiting
Registry status
NA
Development phase
1,500
Enrollment target
1
Study location

NCT06260683: Recruiting NA study of Cigarette Smoking-Related Carcinoma, sponsored by Ohio State University Comprehensive Cancer Center.

NCT06260683 is a NA study of Cigarette Smoking-Related Carcinoma that is actively recruiting participants, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 1,500 participants, above the 396-participant average among 21 other Cigarette Smoking-Related Carcinoma trials with a reported enrollment target (279% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06260683, a NA study of Cigarette Smoking-Related Carcinoma, is actively recruiting participants, sponsored by Ohio State University Comprehensive Cancer Center.

RECRUITING
Registry status
NA
Development phase
1,500 participants
Enrollment target
1
Study location

Study Summary

This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers. ECs may reduce cigarette craving and withdrawal symptoms, increase motivation and confidence to stop cigarette smoking, and decrease cigarette smoking and dependence. By comparing participants' preferred flavor ECs (PEC) to tobacco flavor ECs (TEC) to NRT, researchers hope to determine the effect of EC flavors on appeal and use and learn how ECs affect smoking behaviors and health.

Primary Outcome

Self-reported 7-day point prevalence abstinence (no cigarettes, not even a puff, in the previous 7 days), any reported use of ECs or NRT over the past 7 days, and an exhaled CO reading of ≤6ppm.

Interventions

  • OTHER Questionnaire Administration
  • DRUG Nicotine Replacement
  • DEVICE Vaping

Study Locations (1)

Ohio

  • Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2024-04-10
Est. Completion 2028-04-12
Phase NA

What NCT06260683 shows while recruiting

NCT06260683 is an interventional study that assigns participants to a tested intervention. Its 1,500 participants enrollment target places it among the larger protocols in the corpus, above the 396-participant average among 21 other Cigarette Smoking-Related Carcinoma trials with a reported enrollment target (279% higher).

The record links to 1 condition, with Cigarette Smoking-Related Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Questionnaire Administration is the first listed.

NCT06260683 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT06260683 about?

NCT06260683 is a clinical study titled "A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior". This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers. ECs may reduce cigarette craving and withdrawal symptoms, increase motivation an...

What is the current status of trial NCT06260683?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,500 participants. The study started on 2024-04-10. Estimated completion is 2028-04-12.

What conditions does trial NCT06260683 study?

This clinical trial studies the following conditions: Cigarette Smoking-Related Carcinoma.

What interventions are being tested in trial NCT06260683?

The interventions under investigation include: Questionnaire Administration (OTHER), Nicotine Replacement (DRUG), Vaping (DEVICE).

Who is sponsoring clinical trial NCT06260683?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06260683 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cigarette Smoking-Related Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06260683's enrollment target sits among peer trials

1,500 3rd of 21 higher than 19 of 21 other Cigarette Smoking-Related Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cigarette Smoking-Related Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06260683, the US trial registry maintained by the National Library of Medicine. NCT06260683 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.