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NCT06448351 · ClinicalTrials.gov registry record · NA
Manipulating E-Cigarette Nicotine to Promote Public Health
A NA study of Tobacco-Related Carcinoma, sponsored by Ohio State University Comprehensive Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 350
- Enrollment target
- 1
- Study location
NCT06448351: Recruiting NA study of Tobacco-Related Carcinoma, sponsored by Ohio State University Comprehensive Cancer Center.
NCT06448351 is a NA study of Tobacco-Related Carcinoma that is actively recruiting participants, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 350 participants, below the 1,474-participant average among 10 other Tobacco-Related Carcinoma trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06448351, a NA study of Tobacco-Related Carcinoma, is actively recruiting participants, sponsored by Ohio State University Comprehensive Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 350 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial explores the manipulation of e-cigarette (EC) nicotine to promote public health. Researchers are trying to understand and gather information about how the strength, form, and structure of nicotine in products play a significant role in their potential for addiction and how they might affect health risks. The information gained from this study may allow researchers to understand how these aspects of nicotine influence the potential for addiction, how people puff on ECs, how the body processes nicotine, and any potential harmful effects it might have on health. Exploring these specific characteristics of nicotine may also determine if an EC product standard could help identify optimal nicotine levels for users.
Primary Outcome
Blood nicotine samples will be assayed using liquid chromatography tandem mass spectrometry (LC-MS/MS) with deuterated internal standards.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Survey Administration
- PROCEDURE Carbon Monoxide Measurement
- OTHER Vaping session
Study Locations (1)
Ohio
- Ohio State University Comprehensive Cancer Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 350 participants |
| Start Date | 2024-05-20 |
| Est. Completion | 2027-05-20 |
| Phase | NA |
What NCT06448351 shows while recruiting
NCT06448351 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 1,474-participant average among 10 other Tobacco-Related Carcinoma trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Tobacco-Related Carcinoma appearing as the primary indexed condition, and to 4 interventions - of which Biospecimen Collection is the first listed.
NCT06448351 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06448351 about?
NCT06448351 is a clinical study titled "Manipulating E-Cigarette Nicotine to Promote Public Health". This clinical trial explores the manipulation of e-cigarette (EC) nicotine to promote public health. Researchers are trying to understand and gather information about how the strength, form, and structure of nicotine in products play a significant role in their potential for addiction and how they m...
What is the current status of trial NCT06448351?
This trial is currently recruiting. It is a NA study. The enrollment target is 350 participants. The study started on 2024-05-20. Estimated completion is 2027-05-20.
What conditions does trial NCT06448351 study?
This clinical trial studies the following conditions: Tobacco-Related Carcinoma.
What interventions are being tested in trial NCT06448351?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Carbon Monoxide Measurement (PROCEDURE), Vaping session (OTHER).
Who is sponsoring clinical trial NCT06448351?
This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06448351 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco-Related Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06448351's enrollment target sits among peer trials
350 7th of 10 higher than 4 of 10 other Tobacco-Related Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco-Related Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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