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NCT06315881 · ClinicalTrials.gov registry record · Phase 2

Informing Oral Nicotine Pouch Regulations to Promote Public Health

A Phase 2 study of Tobacco-Related Carcinoma, sponsored by Ohio State University Comprehensive Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
160
Enrollment target
1
Study location

NCT06315881 is a Phase 2 study of Tobacco-Related Carcinoma that is actively recruiting participants, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 160 participants, below the 1,493-participant average among 10 other Tobacco-Related Carcinoma trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06315881, a Phase 2 study of Tobacco-Related Carcinoma, is actively recruiting participants, sponsored by Ohio State University Comprehensive Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

This clinical trial evaluates the characteristics of oral nicotine pouches (ONPs) to determine if they are a comparable substitute to cigarette or smokeless tobacco (ST) products. ONPs contain nicotine but no tobacco and are used primarily by adult tobacco uses in the United States (US). ONPs are recognized by the Food and Drug Administration as having lower risk than combustible cigarettes and are approved as a modified risk tobacco product. While ONPs have lower toxic risk than other tobacco products, acute and longer term harm related to their use has not been studied. Information gathered from this study may identify product characteristics of ONPs that improve successful switching from high-risk cigarettes or ST to lower risk ONPs.

Conditions Studied

Interventions

  • PROCEDURE Biospecimen Collection
  • DRUG Nicotine Oral Pouch
  • DRUG Cigarette

Study Locations (1)

Ohio

  • Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2025-01-13
Est. Completion 2028-08-31
Phase Phase 2

What the Registry Record Tells You About NCT06315881

The ClinicalTrials.gov registry entry for NCT06315881 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,493-participant average among 10 other Tobacco-Related Carcinoma trials with a reported enrollment target (89% lower). The listed sponsor is Ohio State University Comprehensive Cancer Center, which has 341 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Tobacco-Related Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Biospecimen Collection is the first listed.

NCT06315881 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06315881 about?

NCT06315881 is a clinical study titled "Informing Oral Nicotine Pouch Regulations to Promote Public Health". This clinical trial evaluates the characteristics of oral nicotine pouches (ONPs) to determine if they are a comparable substitute to cigarette or smokeless tobacco (ST) products. ONPs contain nicotine but no tobacco and are used primarily by adult tobacco uses in the United States (US). ONPs are re...

What is the current status of trial NCT06315881?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2025-01-13. Estimated completion is 2028-08-31.

What conditions does trial NCT06315881 study?

This clinical trial studies the following conditions: Tobacco-Related Carcinoma.

What interventions are being tested in trial NCT06315881?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Nicotine Oral Pouch (DRUG), Cigarette (DRUG).

Who is sponsoring clinical trial NCT06315881?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06315881 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.