National Institutes of Health Clinical Center (CC)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institutes of Health Clinical Center (CC) sits in the top decile of US sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count).

338 total trials 22 currently recruiting 272 completed early-phase tilt top decile by trial count

National Institutes of Health Clinical Center (CC): 338 sponsored US clinical trials, 22 recruiting.

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Top-decile sponsor footprint

National Institutes of Health Clinical Center (CC) ranks in the top decile of sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

272 of 308 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

338 total, page 4 of 7

COMPLETED Phase 3

Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease

NCT00393250

COMPLETED

Effects of Antibodies to White Blood Cells on Platelet Transfusion Patients

NCT00460122

TERMINATED Phase 2

Lenalidomide, Sunitinib, and Cyclophosphamide in Treating Patients With Stage IV Eye Melanoma

NCT00482911

COMPLETED

Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders

NCT00433862

COMPLETED

Research Participants' Views on the Ethics of Clinical Research

NCT00457041

COMPLETED Phase 1

Education Program to Manage Emotional Stress of Stem Cell Transplant Recipients and Their Caregivers

NCT00423774

COMPLETED Early Phase 1

Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer

NCT00436410

COMPLETED

Development of Serologic Assays for Human Herpes Virus-8

NCT00395278

COMPLETED

Decision-Making of Hispanics and African-Americans With HIV/AIDS Participating in Clinical Trials

NCT00394004

COMPLETED Phase 4

Effectiveness of Short-Course Versus Standard Antibiotic Therapy in ICU Patients

NCT00410527

COMPLETED Phase 1

Vaccine Therapy, Incomplete Freund's Adjuvant, and GM-CSF in Treating Patients With HIV

NCT00381875

COMPLETED

Transplant-Related Accelerated Progression of Hepatitis C

NCT00368225

COMPLETED Phase 1

ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer

NCT00387608

COMPLETED

Iron Replacement in Blood Donors

NCT00327067

COMPLETED

Cardiomyopathy Following Stem Cell Transplantation

NCT00352209

COMPLETED Phase 2

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis

NCT00132015

COMPLETED Phase 1

TNF-Bound Colloidal Gold in Treating Patients With Advanced Solid Tumors

NCT00356980

COMPLETED Phase 1

ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma

NCT00352313

COMPLETED Phase 2

Positron Emission Tomography and CT Scan in Predicting Response in Patients With Metastatic Melanoma or Kidney Cancer Who Are Undergoing Cellular Adoptive Immunotherapy on a Surgery Branch Clinical Trial

NCT00316901

COMPLETED NA

Three Different Types of Thermometers in Measuring Temperature in Young Patients With Fever and Without Fever

NCT00378846

COMPLETED Phase 2

OT-551 Antioxidant Eye Drops to Treat Geographic Atrophy in Age-Related Macular Degeneration

NCT00306488

COMPLETED Phase 2

LMB-2 Immunotoxin and Vaccine Therapy in Treating Patients With Metastatic Melanoma That Cannot Be Removed By Surgery

NCT00295958

COMPLETED Phase 1

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

NCT00303940

COMPLETED Phase 2

Trastuzumab and Pertuzumab in Treating Patients With Unresectable Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Trastuzumab

NCT00301899

COMPLETED Phase 4

Effect of Genetics on Metabolism of Efavirenz

NCT00245986

COMPLETED

Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields

NCT00340054

COMPLETED

Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma

NCT00226304

COMPLETED Phase 1

PEG-Interferon Alfa-2b in Treating Young Patients With Plexiform Neurofibroma

NCT00253474

COMPLETED

Quality of Life in Patients Who Have Undergone Stem Cell Transplant

NCT00128960

COMPLETED Phase 1

Pharmacokinetics of Mycophenolate Mofetil in Healthy Volunteers

NCT00128947

TERMINATED Phase 2

Cyclophosphamide and Fludarabine Followed By an Autologous Lymphocyte Infusion and Interleukin-2 in Treating Patients With Refractory or Recurrent Metastatic Melanoma

NCT00138229

COMPLETED

Gait Adaptations to Passive Dynamic Ankle-Foot Orthosis Use

NCT00115401

COMPLETED

Heart Disease in Sickle Cell Anemia

NCT00113152

COMPLETED Phase 2

Acamprosate to Reduce Symptoms of Alcohol Withdrawal

NCT00106106

COMPLETED Phase 2

Effects of Pet Therapy on Pain in Cancer Patients

NCT00431639

COMPLETED

Sensing of Leg Position and Movement

NCT00100919

COMPLETED Phase 4

Drug Interactions of Echinacea, Ginseng, and Ginkgo Biloba Taken With Lopinavir/Ritonavir in Healthy Volunteers

NCT00103012

COMPLETED

Evaluation of Patients With Critical Illness

NCT00100217

COMPLETED

Views of Cancer Patients Regarding Financial Conflicts of Interest

NCT00097682

COMPLETED

Impact of Move to Clinical Research Center on Physical Activity of Employees

NCT00095485

COMPLETED Phase 1

Carbon Monoxide to Prevent Lung Inflammation

NCT00094406

COMPLETED

The Effect of Sildenafil Citrate (Viagra® (Registered Trademark)) on Brain Blood Flow in Multiple Sclerosis Patients

NCT00094068

COMPLETED

Revising Employee Benefits for the Sake of Health

NCT00097461

COMPLETED Phase 1

Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors

NCT00093444

COMPLETED Phase 1

Paclitaxel and ABI-007 in Treating Patients With Locally Advanced or Metastatic Solid Tumors

NCT00095914

COMPLETED Phase 2

Cyclophosphamide, Fludarabine, and Total-Body Irradiation Followed By Cellular Adoptive Immunotherapy, Autologous Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Metastatic Melanoma

NCT00096382

COMPLETED Phase 1

Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma

NCT00091104

COMPLETED

Effect of Respiratory Motion on Positron Emission Tomography Imaging

NCT00088361

COMPLETED Phase 2

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Unresectable Colorectal Cancer That Has Metastasized to the Liver

NCT00089401

COMPLETED Phase 1

17-Dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in Treating Patients With an Advanced Solid Tumor or Lymphoma

NCT00088868

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What is open in the National Institutes of Health Clinical Center (CC) pipeline

22 recruiting of 338 indexed (7% open); 272 completed (80%).

Phase mix: 17 late (III/IV) vs 121 early (I/II) (early-phase heavy).

Top condition: Healthy (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institutes of Health Clinical Center (CC): open-pipeline peers nationwide

Peers matched on 338 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share National Institutes of Health Clinical Center (CC)Cedars-Sinai Medical CenterOhio State University Comprehensive Cancer CenterNational Institute on Drug Abuse (NIDA)Children's Oncology GroupAlliance for Clinical Trials in OncologyNICHD Neonatal Research NetworkInsmed IncorporatedBaylor Breast Care Center
National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 338 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this National Institutes of Health Clinical Center (CC) page

338 registered trials is a research-attention snapshot, not an endorsement of National Institutes of Health Clinical Center (CC) or any single study.

  • 22 of National Institutes of Health Clinical Center (CC)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institutes of Health Clinical Center (CC) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institutes of Health Clinical Center (CC) pipeline card: 338 registered trials from official public datasets.Report a data error.