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NCT00093444 · ClinicalTrials.gov registry record · Phase 1

Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors

A Phase 1 study of Metastatic Cancer and Liver Cancer, sponsored by National Institutes of Health Clinical Center (CC).

Completed
Registry status
Phase 1
Development phase
30
Enrollment target
2
Study locations

NCT00093444 is a Phase 1 study of Metastatic Cancer and Liver Cancer that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 30 participants, below the 444-participant average among 109 other Metastatic Cancer trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT00093444, a Phase 1 study of Metastatic Cancer and Liver Cancer, has completed, sponsored by National Institutes of Health Clinical Center (CC).

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with liposomal doxorubicin may increase the effectiveness of the drug and kill more tumor cells. PURPOSE: This phase I trial is studying the best dose of liposomal doxorubicin when given with radiofrequency ablation in treating patients with primary or metastatic liver tumors.

Interventions

  • DRUG lyso-thermosensitive liposomal doxorubicin
  • PROCEDURE radiofrequency ablation

Study Locations (2)

Maryland

  • Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office - Bethesda

Other

  • Queen Mary Hospital - Hong Kong - Hong Kong

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2004-09
Est. Completion 2010-01
Phase Phase 1

What the Registry Record Tells You About NCT00093444

The ClinicalTrials.gov registry entry for NCT00093444 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 444-participant average among 109 other Metastatic Cancer trials with a reported enrollment target (93% lower). The listed sponsor is National Institutes of Health Clinical Center (CC), which has 338 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Metastatic Cancer appearing as the primary indexed condition, and to 2 interventions - of which lyso-thermosensitive liposomal doxorubicin is the first listed.

NCT00093444 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Maryland, Other.

Frequently Asked Questions

What is clinical trial NCT00093444 about?

NCT00093444 is a clinical study titled "Heat Activated Liposomal Doxorubicin and Radiofrequency Ablation in Treating Patients With Primary or Metastatic Liver Tumors". RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with liposomal doxorubicin m...

What is the current status of trial NCT00093444?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2004-09. Estimated completion is 2010-01.

What conditions does trial NCT00093444 study?

This clinical trial studies the following conditions: Metastatic Cancer, Liver Cancer.

What interventions are being tested in trial NCT00093444?

The interventions under investigation include: lyso-thermosensitive liposomal doxorubicin (DRUG), radiofrequency ablation (PROCEDURE).

Who is sponsoring clinical trial NCT00093444?

This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00093444 being conducted?

This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.