National Institutes of Health Clinical Center (CC)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institutes of Health Clinical Center (CC) sits in the top decile of US sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count).

338 total trials 22 currently recruiting 272 completed early-phase tilt top decile by trial count

National Institutes of Health Clinical Center (CC): 338 sponsored US clinical trials, 22 recruiting.

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Top-decile sponsor footprint

National Institutes of Health Clinical Center (CC) ranks in the top decile of sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

272 of 308 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

338 total, page 3 of 7

COMPLETED

Physical and Emotional Health of Caregivers for People Who Have Had Stem Cell Transplants

NCT01468857

COMPLETED

Studying Childhood-Onset Hemidystonia

NCT01432899

COMPLETED Phase 1

Effects of Rapid-Resisted Exercise and Bright Light Therapy on Ambulatory Adults With Traumatic Brain Injury

NCT01175993

COMPLETED

Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV Infection

NCT01350648

TERMINATED Phase 3

Treadmill Training at Constant or Different Speeds for People With Traumatic Brain Injury

NCT01419522

TERMINATED Phase 3

Effect of Music on Pain and Anxiety After Surgery

NCT01409044

COMPLETED

Stereophotogrammetry of the Torso in Healthy Individuals and Patients With Scoliosis, Chest Wall Deformations, or Obesity

NCT01352949

COMPLETED Phase 1

Effect of Aerobic Exercise Training on Cardiorespiratory Function in Patients With Traumatic Brain Injury

NCT01294332

COMPLETED

Testing Devices That Involve the Sense of Touch in Subjects With Traumatic Brain Injury

NCT01404494

TERMINATED

Long-term Clinical Correlates of Traumatic Brain Injury

NCT01132898

TERMINATED Phase 1

Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting Beads

NCT01336985

TERMINATED

Quantifying and Understanding the Signs and Symptoms of Fever

NCT01287143

TERMINATED Phase 1

Microplasmin Intravitreal Administration in Participants With Uveitic Macular Edema

NCT01194674

TERMINATED NA

Comparing Xperguide vs. Conventional Methods During Percutaneous Image Guided Procedures

NCT01287013

COMPLETED

Evaluating Supportive Care for Children With Cancer: A Multi-Institutional Survey Study of Pediatric Oncology Patients and Parents

NCT01273194

COMPLETED Phase 1

Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study

NCT01253083

COMPLETED

Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection

NCT01150721

TERMINATED Phase 1

Cell Therapy for Metastatic Melanoma Using CD8 Enriched Tumor Infiltrating Lymphocytes

NCT01236573

COMPLETED Phase 1

A Safety and Tolerability Study of Nitazoxanide in HIV-HCV Treatment Failures

NCT01185028

COMPLETED

Noninvasive Imaging of Heart Failure: A Pilot Study

NCT01160471

COMPLETED Phase 1

The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers

NCT01148004

COMPLETED

Research Participant Perception of Care Project: Part II: Fielding and Validation of the Research Participant Perception Survey Derived From Focus Group-Identified Key Dimensions of the Research Participant Experience

NCT01129869

COMPLETED Phase 1

Physical, Functional and Neural Effects of Two Lower Extremity Exercise Protocols in Children With Cerebral Palsy

NCT01086670

TERMINATED

Collection of Bone Marrow From Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) Products

NCT01071577

COMPLETED

A Cross-Cultural Assessment of the Motivations of Healthy Participants in Phase I Research

NCT01485250

COMPLETED

X-Ray Mammography Standard of Care Protocol

NCT01052740

COMPLETED

Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteer

NCT00978003

COMPLETED

Evaluation of Outcome Measures for Patients Diagnosed With Traumatic Brain Injury

NCT01020318

COMPLETED

Phenomenological Study of Psycho-Socio-Spiritual Healing in the Context of Chronic or Life-Threatening Illness

NCT01077414

COMPLETED Phase 1

Drug Interaction Study Between Inhaled Beclomethasone and Protease Inhibitors in Healthy Volunteers

NCT00936793

TERMINATED NA

NIH Substudy of AIN457 (Anti-IL-17 Monoclonal Antibody) for Treatment of Moderate to Severe Crohn's Disease

NCT00936585

COMPLETED Phase 1

Probiotic Ingestion and Isoagglutinin Titers

NCT00891787

COMPLETED Phase 2

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

NCT00826241

COMPLETED

Evaluating the Quality of Different Methods of Obtaining Informed Consent

NCT00794729

COMPLETED Phase 2

Problem-Solving Education for Caregivers and Patients During Stem Cell Transplant

NCT00766883

TERMINATED

Evaluation of Assessments of Motor Performance, Physical Impairments and Functional Abilities

NCT00747955

COMPLETED Phase 2

Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidism

NCT00743782

COMPLETED

Research Participants Perceptions of Their Experience in Clinical Studies

NCT00729534

COMPLETED Phase 2

Aerobic Exercise in Patients With Pulmonary Hypertension

NCT00678821

TERMINATED Phase 2

Gene-Modified Lymphocytes, High-Dose Aldesleukin, and Vaccine Therapy in Treating Patients With Progressive or Recurrent Metastatic Cancer

NCT00704938

COMPLETED

Communicating a Cancer Diagnosis-Current Methods and Their Effects

NCT00674804

COMPLETED Phase 1

Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma

NCT00734890

COMPLETED

Parental Permission and Adolescent Assent and Decision-Making in Clinical Research

NCT00571311

TERMINATED Phase 1

Lymphocyte Infusions for the Treatment of HIV-Infected Patients Failing Anti-HIV Therapy

NCT00559416

TERMINATED Phase 2

Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain

NCT00550654

COMPLETED

Choosing Healthful Interventions

NCT00537706

COMPLETED Phase 1

Positron Emission Tomography Using [18F]-Labeled Substance P Antagonist Receptor Quantifier in Finding Disease in Patients With Pancreatic Cancer

NCT00547612

COMPLETED Phase 1

Fenretinide Lym-X-Sorb™ in Treating Patients With Recurrent or Resistant Solid Tumors or Lymphoma

NCT00589381

COMPLETED

Effects of Stem Cell Transplantation on Bacteria in the Mouth

NCT00476450

COMPLETED NA

Drug Interaction Study of Lopinavir/Ritonavir and Gemfibrozil

NCT00474201

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What is open in the National Institutes of Health Clinical Center (CC) pipeline

22 recruiting of 338 indexed (7% open); 272 completed (80%).

Phase mix: 17 late (III/IV) vs 121 early (I/II) (early-phase heavy).

Top condition: Healthy (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institutes of Health Clinical Center (CC): open-pipeline peers nationwide

Peers matched on 338 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share National Institutes of Health Clinical Center (CC)Cedars-Sinai Medical CenterOhio State University Comprehensive Cancer CenterNational Institute on Drug Abuse (NIDA)Children's Oncology GroupAlliance for Clinical Trials in OncologyNICHD Neonatal Research NetworkInsmed IncorporatedBaylor Breast Care Center
National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 338 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this National Institutes of Health Clinical Center (CC) page

338 registered trials is a research-attention snapshot, not an endorsement of National Institutes of Health Clinical Center (CC) or any single study.

  • 22 of National Institutes of Health Clinical Center (CC)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institutes of Health Clinical Center (CC) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institutes of Health Clinical Center (CC) pipeline card: 338 registered trials from official public datasets.Report a data error.