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Enhancing Motor Task Training by Action Observation Watching Others Perform the Task
NCT00393432 · View on ClinicalTrials.gov ↗
Study Summary
This study will determine how the brain learns a new motor task when the subject practices the task and watches others perform it (action observation) at the same time. Healthy normal volunteers between 18 and 55 years of age may be eligible for this study. Candidates are screened with a medical history, general and neurological exam, and a brain MRI if one has not been done within 12 months of entering the study. Participants undergo one or both of the following experiments: 1. Effect of Transcranial Magnetic Stimulation on Motor Training and Action Observation Subjects participate in at least 12 4-hour test sessions, separated by at least 1 day. Each session includes the following: * Functional MRI (fMRI): MRI scanning uses a magnetic field and radio waves to produce images of the brain. For fMRI, the subject performs tasks during the scan to allow researchers to see brain changes that occur during performance of the activity. * Transcranial magnetic stimulation (TMS): For this test, a wire coil is held on the scalp. A brief electrical current passes through the coil to stimulate the brain. The stimulation may cause a twitch in muscles of the face, arm, or leg, and the subject may hear a click and feel a pulling sensation on the skin under the coil. During the stimulation, the subject is asked to: 1) perform the training task (make brisk thumb movements); 2) watch a video showing the hand of another person performing the same task; and 3) perform the task and watch the video at the same time, synchronizing his or her movements with those observed in the video. * Surface electromyography: Electrodes are filled with a conductive gel and taped to the skin over a hand muscle to measure the electrical activity of the muscle. * Behavioral measurements: Evaluation of learned movement tasks. * Questionnaires to test attention, fatigue and mood before, during and after each test session. 2. Effect of Pharmacological Agents on Motor Training and Action
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2006-10-18 |
| Est. Completion | 2008-07-18 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00393432
The ClinicalTrials.gov registry entry for NCT00393432 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 339 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Motor Memory appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00393432 reports 1 study location spanning 1 distinct geographic area — top geographies include Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00393432 about?
NCT00393432 is a clinical study titled "Enhancing Motor Task Training by Action Observation Watching Others Perform the Task". This study will determine how the brain learns a new motor task when the subject practices the task and watches others perform it (action observation) at the same time. Healthy normal volunteers between 18 and 55 years of age may be eligible for this study. Candidates are screened with a medical hi...
What is the current status of trial NCT00393432?
This trial is currently completed. The enrollment target is 40 participants. The study started on 2006-10-18. Estimated completion is 2008-07-18.
What conditions does trial NCT00393432 study?
This clinical trial studies the following conditions: Motor Memory. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT00393432?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 339 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00393432 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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