Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00396890 · ClinicalTrials.gov registry record
Enhancing Brain Activity With Magnetic Stimulation
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 72
- Enrollment target
NCT00396890: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00396890 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 72 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00396890 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 72 participants
- Enrollment target
Study Summary
This study will determine whether stimulation of the right side of the brain with repetitive transcranial magnetic stimulation (rTMS) followed by stimulation of the left side with theta burst stimulation (TBS) can temporarily change brain activity and improve hand movements in subjects more than has recently been achieved with rTMS alone. For rTMS, a wire coil is held on the patient's scalp. A brief electrical current is passed through the coil, creating a magnetic pulse that stimulates the brain. The subject hears a click and may feel a pulling sensation on the skin under the coil. There may be a twitch in the muscles of the face, arm or leg. The subject may be asked to tense certain muscles slightly or perform other simple actions. The effect of TMS on the muscles is detected with small metal disk electrodes taped to the skin of the arms or legs. This study uses two kinds of rTMS. In one (Hz rTMS), magnetic pulses are given once per second for a period of 20 minutes; in the other (TBS), a series of pulses are given in bursts, each lasting 2 seconds, for a period of 3 minutes. Healthy normal volunteers between 18 and 55 years of age may be eligible for this study. Participants undergo the following procedures during three visits to the NIH Clinical Center: Visit 1: Participants receive either real or sham rTMS applied on the right side of the brain followed by real or sham TBS applied on the left side of the brain. In addition, subjects undergo the following: " Pinch force: Subjects press a wedged instrument between the thumb and index finger as hard as they can during several trials every 10 seconds. " Speed tapping: Subjects press a key on a computer keyboard as quickly as possible for 10 seconds, repeated for several trials. " Simple reaction time: Subjects respond as quickly as possible to a "go" signal presented on a computer monitor by performing a quick wrist movement. " Electromyography: Subjects' muscle activity is recorded using electrodes (small
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2006-11-03 |
| Est. Completion | 2008-12-15 |
What the finished NCT00396890 record still lists
NCT00396890 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 72 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00396890 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00396890 about?
NCT00396890 is a clinical study titled "Enhancing Brain Activity With Magnetic Stimulation". This study will determine whether stimulation of the right side of the brain with repetitive transcranial magnetic stimulation (rTMS) followed by stimulation of the left side with theta burst stimulation (TBS) can temporarily change brain activity and improve hand movements in subjects more than has...
What is the current status of trial NCT00396890?
This trial is currently completed. The enrollment target is 72 participants. The study started on 2006-11-03. Estimated completion is 2008-12-15.
Who is sponsoring clinical trial NCT00396890?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02359253 · 72 participants · NA
Robot Aided Rehabilitation - Intervention
- NCT02962661 · 72 participants · Phase 1
Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
- NCT03113643 · 72 participants · Phase 1
SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
- NCT03187535 · 72 participants · NA
Effect of TEAS on PONV After Spinal Surgery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI