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NCT00307385 · ClinicalTrials.gov registry record
Transcranial Direct Current Stimulation to Improve Hand Movement in Stroke Patients
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 82
- Enrollment target
NCT00307385: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00307385 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 82 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00307385 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 82 participants
- Enrollment target
Study Summary
This study will examine whether hand movement in stroke patients can be improved by applying electrical stimulation to the side of the brain affected by the stroke. It will compare the effects of similar brain stimulations in stroke patients and healthy volunteers. Healthy, right-handed normal volunteers and stroke patients between 18 and 80 years of age may be eligible for this study. Patients' stroke must have occurred at least 3 months before entering the study and affect one side of the brain only. Candidates are screened with a medical history, brain MRI, and evaluation of memory and attention span. Pregnant women are excluded from the study. The study involves seven 2-day sessions over the course of about 8 weeks, with each session separated by at least 1 week. During each session participants practice a pattern of hand movements and their accuracy in performing the movements is evaluated before and after brain electrical stimulation. The movements include a complex finger sequence, a simple finger sequence, a peg test (placing wooden pegs in holes on a board), a hand function test (turning over cards, picking up small objects with one hand and placing them in a can, picking up small objects with a spoon and placing them in a can, stacking checkers, moving light cans, and moving heavy cans), and a box and block test (picking up and moving blocks from one box to another). The first day of each 2-day session lasts about 5 hours and includes the following: * TMS measurements: A wire coil is held on the scalp, and a brief electrical current is passed through the coil, creating a magnetic pulse that stimulates the brain. During the stimulation, the subject may be asked to tense certain muscles slightly or perform other simple actions. The stimulation may cause a twitch in muscles of the face, arm, or leg, and the subject may hear a click and feel a pulling sensation on the skin under the coil. * tDCS: Small, wet sponge electrodes are applied to the head - one a
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2006-03-23 |
| Est. Completion | 2008-03-27 |
What the finished NCT00307385 record still lists
NCT00307385 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 82 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00307385 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00307385 about?
NCT00307385 is a clinical study titled "Transcranial Direct Current Stimulation to Improve Hand Movement in Stroke Patients". This study will examine whether hand movement in stroke patients can be improved by applying electrical stimulation to the side of the brain affected by the stroke. It will compare the effects of similar brain stimulations in stroke patients and healthy volunteers. Healthy, right-handed normal volu...
What is the current status of trial NCT00307385?
This trial is currently completed. The enrollment target is 82 participants. The study started on 2006-03-23. Estimated completion is 2008-03-27.
Who is sponsoring clinical trial NCT00307385?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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