National Institute of Mental Health (NIMH)
National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.
Trial Pipeline
343 total, page 2 of 7
Identifying Decision Making Parameters in Healthy Volunteers and Anxiety Patients
NCT05092971
Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders
NCT04317118
Antidepressant Effects of TS-161 in Treatment-Resistant Depression
NCT04821271
Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 Pandemic
NCT04823988
Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine
NCT04711005
Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
NCT04684615
Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses
NCT04377100
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
NCT04339790
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
NCT03958630
Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions
NCT03912428
Estrogen Receptor Beta and Mood
NCT03689543
Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)
NCT03861000
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
NCT03289923
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
NCT02743377
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
NCT03507218
Development of Non-Invasive Brain Stimulation Techniques
NCT03351764
Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)
NCT03324646
Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core
NCT03092687
Effect of Transcranial Magnetic Stimulation to the Frontoparietal Attention Network on Anxiety Potentiated Startle
NCT03027414
Novel Positron Emission Tomography (PET) Radiotracer to Image Phosphodiesterase-4B (PDE4B)
NCT03030391
Use of the Ask Suicide-Screening Questions (ASQ) in Pediatric Outpatient Settings
NCT02830334
Main Study: Influence on Plasticity of Brain Temperature Sub-Study: Phase Triggered Paired Associative Stimulation (PAS)
NCT02363296
Evaluation of a Novel PET Radioligand to Image OGA
NCT03632226
Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder
NCT02484456
Spatial Context and Fear Learning
NCT02423044
Checking Out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress
NCT02423031
PET Imaging in Chronic Traumatic Encephalopathy
NCT02211820
Specific PET Radioligand Binding to Translocator Protein
NCT02181582
Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
NCT02153944
Ask Suicide-Screening Questions to Everyone in Medical Settings (asQ em): Development of a Suicide Risk Screening Instrument for Adult Medical Inpatients
NCT02140177
Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People
NCT02147392
Evaluation of a Novel Positron Emission Tomography (PET Radiotracer for TARP Gamma-8
NCT02108015
Imaging and Genetic Investigation of Learning and Decision Making
NCT01950377
Validation of the Ask Suicide-Screening Questions (ASQ) in the Inpatient Medical Setting
NCT02050867
Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?
NCT02049385
PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX
NCT02230592
Evaluation of Two Radioactive Chemicals to Image mGluR5 Receptors in Brain
NCT01896843
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
NCT01887132
Brain Inflammation in Major Depressive Disorder Background
NCT01851356
Effects of Atypical Antipsychotics on Brain Function in Children and Teens With Conduct Disorders
NCT01867398
Study of [11C]DPA-713 for Temporal Lobe Epilepsy
NCT01793532
A Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults
NCT01778478
Near Infrared Spectroscopy in Children With Autism and ADHD
NCT01730079
Daily Intranasal Oxytocin for Childhood-Onset Schizophrenia
NCT01712646
Translocator Protein and Inflammation After Traumatic Brain Injury
NCT01547780
Mild Neurocognitive Disorder in HIV Infection of the Brain
NCT01547754
Imaging of Brain Receptors Using (11C)mGlu1
NCT01420952
Imaging of CB1 Receptors Using (11C)SD5024
NCT01399398
(18F)FCWAY and the Blood-Brain Barrier
NCT01386476
Study of Toddlers With Language Delay
NCT01339767
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 61 |
| Phase 2 | 45 |
| Phase 3 | 8 |
| Phase 4 | 21 |
Therapeutic Areas
What the Pipeline for National Institute of Mental Health (NIMH) Shows
According to the ClinicalTrials.gov registry, National Institute of Mental Health (NIMH) is linked to 343 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 256 are already marked complete, representing roughly 75% of the total.
The phase mix for National Institute of Mental Health (NIMH) reports 29 late-stage studies (Phase 3 and Phase 4 combined) and 106 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Mental Health (NIMH) is Healthy with 21 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.