National Institute of Mental Health (NIMH)
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, National Institute of Mental Health (NIMH) sits in the top decile of US sponsors by registered trial count (#103 of 15,742 sponsors by registered trial count).
National Institute of Mental Health (NIMH): 343 sponsored US clinical trials, 42 recruiting.
National Institute of Mental Health (NIMH) sponsors 343 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 256 completed. 29 of these trials are in Phase 3-4 (later-stage) and 106 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 21 trials.
Top-decile sponsor footprint
National Institute of Mental Health (NIMH) ranks in the top decile of sponsors by registered trial count (#103 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
256 of 296 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
343 total, page 2 of 7
Identifying Decision Making Parameters in Healthy Volunteers and Anxiety Patients
NCT05092971
Ask Suicide-Screening Questions (ASQ) for Youth With Autism Spectrum and Neurodevelopmental Disorders
NCT04317118
Antidepressant Effects of TS-161 in Treatment-Resistant Depression
NCT04821271
Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 Pandemic
NCT04823988
Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine
NCT04711005
Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
NCT04684615
Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses
NCT04377100
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
NCT04339790
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
NCT03958630
Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions
NCT03912428
Estrogen Receptor Beta and Mood
NCT03689543
Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)
NCT03861000
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
NCT03289923
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
NCT02743377
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
NCT03507218
Development of Non-Invasive Brain Stimulation Techniques
NCT03351764
Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)
NCT03324646
Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core
NCT03092687
Effect of Transcranial Magnetic Stimulation to the Frontoparietal Attention Network on Anxiety Potentiated Startle
NCT03027414
Novel Positron Emission Tomography (PET) Radiotracer to Image Phosphodiesterase-4B (PDE4B)
NCT03030391
Use of the Ask Suicide-Screening Questions (ASQ) in Pediatric Outpatient Settings
NCT02830334
Main Study: Influence on Plasticity of Brain Temperature Sub-Study: Phase Triggered Paired Associative Stimulation (PAS)
NCT02363296
Evaluation of a Novel PET Radioligand to Image OGA
NCT03632226
Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder
NCT02484456
Spatial Context and Fear Learning
NCT02423044
Checking Out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress
NCT02423031
PET Imaging in Chronic Traumatic Encephalopathy
NCT02211820
Specific PET Radioligand Binding to Translocator Protein
NCT02181582
Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
NCT02153944
Ask Suicide-Screening Questions to Everyone in Medical Settings (asQ em): Development of a Suicide Risk Screening Instrument for Adult Medical Inpatients
NCT02140177
Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People
NCT02147392
Evaluation of a Novel Positron Emission Tomography (PET Radiotracer for TARP Gamma-8
NCT02108015
Imaging and Genetic Investigation of Learning and Decision Making
NCT01950377
Validation of the Ask Suicide-Screening Questions (ASQ) in the Inpatient Medical Setting
NCT02050867
Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?
NCT02049385
PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX
NCT02230592
Evaluation of Two Radioactive Chemicals to Image mGluR5 Receptors in Brain
NCT01896843
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
NCT01887132
Brain Inflammation in Major Depressive Disorder Background
NCT01851356
Effects of Atypical Antipsychotics on Brain Function in Children and Teens With Conduct Disorders
NCT01867398
Study of [11C]DPA-713 for Temporal Lobe Epilepsy
NCT01793532
A Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults
NCT01778478
Near Infrared Spectroscopy in Children With Autism and ADHD
NCT01730079
Daily Intranasal Oxytocin for Childhood-Onset Schizophrenia
NCT01712646
Translocator Protein and Inflammation After Traumatic Brain Injury
NCT01547780
Mild Neurocognitive Disorder in HIV Infection of the Brain
NCT01547754
Imaging of Brain Receptors Using (11C)mGlu1
NCT01420952
Imaging of CB1 Receptors Using (11C)SD5024
NCT01399398
(18F)FCWAY and the Blood-Brain Barrier
NCT01386476
Study of Toddlers With Language Delay
NCT01339767
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 61 |
| Phase 2 | 45 |
| Phase 3 | 8 |
| Phase 4 | 21 |
Therapeutic Areas
What is open in the National Institute of Mental Health (NIMH) pipeline
42 recruiting of 343 indexed (12% open); 256 completed (75%).
Phase mix: 29 late (III/IV) vs 106 early (I/II) (early-phase heavy).
Top condition: Healthy (21 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
National Institute of Mental Health (NIMH): open-pipeline peers nationwide
Peers matched on 343 registered trials and 12% open enrollment, not the therapeutic-area sidebar.
National Institute of Mental Health (NIMH) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 343 trials (± recruiting share)
- Children's Oncology Group · 342 trials · 10% recruiting
- Montefiore Medical Center · 345 trials · 19% recruiting
- Ohio State University Comprehensive Cancer Center · 341 trials · 23% recruiting
- Cedars-Sinai Medical Center · 339 trials · 21% recruiting
Sponsors near 12% open enrollment (± trial volume)
- Augusta University · 12% recruiting · 106 trials
- University of Iowa · 12% recruiting · 228 trials
- Daiichi Sankyo · 12% recruiting · 236 trials
- Friends Research Institute · 12% recruiting · 41 trials
Related
What to do with this National Institute of Mental Health (NIMH) page
343 registered trials is a research-attention snapshot, not an endorsement of National Institute of Mental Health (NIMH) or any single study.
- 42 of National Institute of Mental Health (NIMH)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Healthy is the condition National Institute of Mental Health (NIMH) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
National Institute of Mental Health (NIMH) pipeline card: 343 registered trials from official public datasets.Report a data error.