Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 39 of 57

COMPLETED Phase 4

Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids

NCT02111603
COMPLETED Phase 2

Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial

NCT02105415
COMPLETED NA

Fall Recovery Training for Older Adults in Continuous Care Facilities

NCT02173015
COMPLETED NA

Change in Permeability of the Small Intestine After Treatment With Gluten

NCT02098057
COMPLETED Early Phase 1

Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab Therapy

NCT01789827
COMPLETED Phase 2

Pomalidomide or Lenalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma Previously Treated With Lenalidomide

NCT01794039
COMPLETED Phase 1

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3)

NCT02058095
COMPLETED Phase 1

Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)

NCT02086526
COMPLETED

Cochlear Implantation Among Adults and Older Children With Unilateral or Asymmetric Hearing Loss

NCT02105441
COMPLETED NA

Mayo Clinic Traumatic Brain Injury Model System Center: The CONNECT Trial

NCT02088099
COMPLETED Phase 1

Omega-3 Fatty Acids to Combat Sarcopenia

NCT02103842
COMPLETED NA

Individualized Preoperative Rehabilitation Pilot

NCT02082223
COMPLETED NA

Prospective Study to Compare the Efficacy of E.G.Scan to Detect Barrett's Esophagus Compared With Standard Endoscopy

NCT02066233
COMPLETED Phase 1

Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study

NCT02096965
COMPLETED NA

Effects of Chardonnay Seed Flour on Vascular Health

NCT02093455
COMPLETED Phase 1

Impact of Endogenous E2 on SSI and GH Rebound

NCT02026973
COMPLETED Phase 1

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

NCT02020707
COMPLETED Phase 2

Auranofin in Decreasing Pain in Patients With Paclitaxel-Induced Pain Syndrome

NCT02063698
COMPLETED NA

Development of 'Emma'--a Pediatric IBD Quiz

NCT02065089
COMPLETED

Assessing Eye Tracking Features Following Sports-Related Concussion

NCT02103803
COMPLETED

Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.

NCT02162953
COMPLETED NA

Increasing Activity in Liver Transplant Patients

NCT02058498
COMPLETED NA

Dose of Labeled Cholesterol for Kinetics: A Pilot Study

NCT02065817
COMPLETED NA

OB Nest; Redefining Continuity of Care for Expectant Mothers

NCT02082275
COMPLETED NA

Cardiac Vascular Reconstruction DynaCT for TAVI Procedures

NCT02031796
COMPLETED Phase 2

Prospective Evaluation of Budesonide for Prevention of Esophageal Strictures After Endotherapy

NCT02069847
TERMINATED

Liver and Biliary Tumor Tissue Registry

NCT02917759
COMPLETED Early Phase 1

18F-DOPA-PET in Planning Surgery in Patients With Gliomas

NCT02020720
COMPLETED Phase 2

Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT02086552
COMPLETED Phase 1

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2)

NCT01970176
COMPLETED Phase 4

Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose

NCT02009722
COMPLETED Phase 4

Study of Arm and Putter Movement in Golfers With Golfer's Cramp

NCT02032758
COMPLETED NA

Enhancing Gluteus Maximus Recruitment

NCT02042937
COMPLETED Phase 4

Short Bowel Syndrome and Teduglutide Versus Placebo

NCT02099084
COMPLETED

A Comparison of Large Diameter Metal Heads vs. Small Diameter Metal Heads vs/ Dual Mobility Total Hip Replacements

NCT02049892
COMPLETED

Biomarker Feedback to Motivate Tobacco Cessation in Pregnant ALaska Native Women: Phase 2

NCT02018640
COMPLETED Phase 2

18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy

NCT01991977
COMPLETED Early Phase 1

Kinesio Taping Effectiveness on Idiopathic Toe Walking

NCT02025582
COMPLETED Phase 2

Regional Prophylactic Vancomycin in Revision Total Knee Replacement

NCT02020031
COMPLETED Early Phase 1

Vaccine Therapy in Treating Patients With Recurrent Glioblastoma

NCT03360708
COMPLETED Early Phase 1

Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

NCT01957956
TERMINATED NA

Treatment of Multifocal Lung Adenocarcinoma

NCT01946100
COMPLETED

Evaluation of the BodyGuardian End-to-end Remote Monitoring Platform in an Outpatient Heart Failure Population

NCT01975402
COMPLETED NA

Feasibility Testing of the Alert for Atrial Fibrillation Program

NCT01988974
COMPLETED NA

A Prospective Trial of an Endoscopic Quality Improvement Project

NCT02325635
COMPLETED Phase 2

SMAC Mimetic LCL161 Alone or With Cyclophosphamide in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT01955434
COMPLETED Phase 2

Serum Bovine Immunoglobulin Protein Isolate in Improving Quality of Life and Post-Operative Recovery in Patients With Gynecological Cancer After Undergoing Surgery

NCT01867606
COMPLETED

Review of Kidney Biopsies of Dent Disease Patients

NCT02022189
COMPLETED Phase 1

CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function

NCT02071602
COMPLETED Phase 2

Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin

NCT02033876
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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

Therapeutic Areas

Healthy 36
Malignant Solid Neoplasm 35
Obesity 31
Breast Cancer 25
Breast Carcinoma 21
Hematopoietic and Lymphatic System Neoplasm 20
Hematopoietic and Lymphoid System Neoplasm 12
Heart Failure 11
Cancer 11
Prostate Carcinoma 9

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Related

Compare saved trials side-by-side

Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.