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NCT01957956 · ClinicalTrials.gov registry record · Early Phase 1
Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
A Early Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 21
- Enrollment target
NCT01957956: Completed Early Phase 1 study, sponsored by Mayo Clinic.
NCT01957956 is a Early Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 21 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01957956, a Early Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 21 participants
- Enrollment target
Study Summary
This pilot clinical trial studies vaccine therapy and temozolomide in treating patients with newly diagnosed glioblastoma. Vaccines made from a person's white blood cells mixed with tumor proteins may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving vaccine therapy and temozolomide may be an effective treatment for glioblastoma.
Primary Outcome
Incidence of significant toxicity will be estimated by the number of patients with significant toxicity divided by the total number of evaluable patients.
Interventions
- OTHER Laboratory Biomarker Analysis
- DRUG Temozolomide
- BIOLOGICAL Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2013-11-11 |
| Est. Completion | 2016-11-16 |
| Phase | Early Phase 1 |
What the finished NCT01957956 record still lists
NCT01957956 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.
NCT01957956 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01957956 about?
NCT01957956 is a clinical study titled "Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma". This pilot clinical trial studies vaccine therapy and temozolomide in treating patients with newly diagnosed glioblastoma. Vaccines made from a person's white blood cells mixed with tumor proteins may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, s...
What is the current status of trial NCT01957956?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 21 participants. The study started on 2013-11-11. Estimated completion is 2016-11-16.
What interventions are being tested in trial NCT01957956?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Temozolomide (DRUG), Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine (BIOLOGICAL).
Who is sponsoring clinical trial NCT01957956?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01957956's enrollment target sits among peer trials
21 1130th of 2000 higher than 845 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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