Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 40 of 57

COMPLETED NA

Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection

NCT02020018

COMPLETED Phase 1

Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.

NCT01956929

COMPLETED NA

Shared Decision Making in the Emergency Department: Chest Pain Choice Trial

NCT01969240

COMPLETED NA

Effect of Transdermal Magnesium Chloride on Quality of Life in Patients With Fibromyalgia

NCT01968772

COMPLETED NA

IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD

NCT02066051

COMPLETED Phase 2

A Pilot Study to Assess the Efficacy of Rituximab Therapy in Treatment Resistant FSGS

NCT01573533

COMPLETED Phase 1

Study to Examine the Effect of Gastric Bypass Surgery on Venlafaxine ER Blood Levels

NCT01867255

COMPLETED

Primary Hyperoxaluria Mutation Genotyping/Phenotyping

NCT02340689

COMPLETED

Phase I/II Cancer Caregiver Interventions to Improve Quality of Life and Prevent Burnout

NCT02166866

COMPLETED Phase 2

Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer

NCT01932697

COMPLETED Phase 1

Lorcaserin for Preventing Weight Gain Among Smokers

NCT02393547

COMPLETED

Validity and Reliability of Outcome Measures in Patients With Cancer of the Head and Neck

NCT01952821

COMPLETED Phase 1

Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers

NCT01950403

COMPLETED Phase 1

Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or Surgery

NCT01888302

COMPLETED Phase 1

Hydroxyproline Influence on Oxalate Metabolism

NCT02038543

COMPLETED Phase 2

Early Levothyroxine Post Radioactive Iodine

NCT01950260

COMPLETED

Role of Intestinal Inflammation in the Pathogenesis of Type 1 Diabetes

NCT01940835

COMPLETED NA

Technology-enhanced Transitional Care for Rural Palliative Care Patients: A Pilot Study

NCT01934413

COMPLETED NA

Healthy Immigrant Families: Working Together To Move More and To Eat Well

NCT01952808

COMPLETED Phase 1

Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue

NCT01944215

COMPLETED NA

Mucosal Impedance and Eosinophilic Esophagitis

NCT01953575

TERMINATED NA

The Affect of Low-Volume Bowel Preparation for Hospitalized Patients Colonoscopies

NCT01978509

COMPLETED Phase 1

Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis

NCT01864018

COMPLETED NA

Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

NCT01924403

COMPLETED

Assessment of Myocardial Tissue Damage in Aortic Stenosis

NCT02101619

COMPLETED Phase 1

Bortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT01936090

COMPLETED Phase 1

Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis

NCT01931007

COMPLETED

Nasal Nitric Oxide Levels in Eosinophilic Esophagitis (EoE)

NCT01929824

COMPLETED NA

Rapid Identification and Susceptibility Testing of Pathogens From Blood Cultures

NCT01898208

COMPLETED NA

Myocardial Infarction Genes (MI-GENES) Study

NCT01936675

COMPLETED Phase 2

LIPS-B: Lung Injury Prevention Study With Budesonide and Beta

NCT01783821

COMPLETED

Personality Profile of Patients With Apical Ballooning Syndrome

NCT01885975

COMPLETED NA

Cardiovascular Effects of Energy Drinks in Healthy Adults

NCT01940822

TERMINATED NA

A Program of Physician Supervision to Improve the Quality of Patient Referrals From Nurse Practitioners and Physician Assistants

NCT01875068

COMPLETED Phase 1

Carfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma

NCT01842308

COMPLETED NA

Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair

NCT03247985

COMPLETED NA

Renal Mass Registry

NCT01887574

COMPLETED Phase 1

The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin Cream

NCT01883102

COMPLETED NA

A Simple Clinical Tool to Help Diagnose Pulmonary Embolism: Phase 1

NCT01898637

COMPLETED Phase 1

Greater Occipital Nerve Injection Study

NCT01988363

COMPLETED

Cryotherapy -BEATS-RF Ablation Trial

NCT01882478

COMPLETED

Early Detection of Broken Hearts in Cancer Patients

NCT02086695

COMPLETED NA

Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy

NCT01880892

COMPLETED Phase 2

Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer

NCT01880528

COMPLETED Phase 2

Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer

NCT01767636

COMPLETED NA

Exploring the Outcomes and Financial Impact of a CBT-I Group Program Provided by Registered Nurses for Adults With Insomnia

NCT02038556

COMPLETED NA

The Effect of Nasal Hair on Nasal Obstruction

NCT01850511

COMPLETED

Examination of the Pancreas in New-onset Diabetes

NCT02001337

COMPLETED NA

Vigorous Exercise for Depressed Smokers

NCT01860924

COMPLETED Phase 1

Impact of Estradiol Addback

NCT01862835

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.