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NCT03360708 · ClinicalTrials.gov registry record · Early Phase 1

Vaccine Therapy in Treating Patients With Recurrent Glioblastoma

A Early Phase 1 study, sponsored by Mayo Clinic.

Completed
Registry status
Early Phase 1
Development phase
20
Enrollment target

NCT03360708: Completed Early Phase 1 study, sponsored by Mayo Clinic.

NCT03360708 is a Early Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 20 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT03360708, a Early Phase 1 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This pilot early phase I trial studies the side effects of vaccine therapy in treating patients with glioblastoma that has come back. Vaccines made from a person's white blood cells mixed with tumor proteins from another person's glioblastoma tumors may help the body build an effective immune response to kill tumor cells. Giving vaccine therapy may work better in treating patients with glioblastoma.

Primary Outcome

Incidence of significant toxicity will be estimated by the number of patients with significant toxicity divided by the total number of evaluable patients.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2013-11-27
Est. Completion 2021-06-02
Phase Early Phase 1
Mayo Clinic

2,844 total trials

What the finished NCT03360708 record still lists

NCT03360708 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT03360708 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03360708 about?

NCT03360708 is a clinical study titled "Vaccine Therapy in Treating Patients With Recurrent Glioblastoma". This pilot early phase I trial studies the side effects of vaccine therapy in treating patients with glioblastoma that has come back. Vaccines made from a person's white blood cells mixed with tumor proteins from another person's glioblastoma tumors may help the body build an effective immune respon...

What is the current status of trial NCT03360708?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2013-11-27. Estimated completion is 2021-06-02.

What interventions are being tested in trial NCT03360708?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT03360708?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03360708's enrollment target sits among peer trials

20 1157th of 2000 higher than 709 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03360708, the US trial registry maintained by the National Library of Medicine. NCT03360708 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.