Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02020720 · ClinicalTrials.gov registry record · Early Phase 1
18F-DOPA-PET in Planning Surgery in Patients With Gliomas
A Early Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 72
- Enrollment target
NCT02020720: Completed Early Phase 1 study, sponsored by Mayo Clinic.
NCT02020720 is a Early Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 72 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (36% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02020720, a Early Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 72 participants
- Enrollment target
Study Summary
This pilot clinical trial studies fluorine F 18 fluorodopa (18F-DOPA)-positron emission tomography (PET) in planning surgery in patients with gliomas. New imaging procedures, such as 18F-DOPA-PET scan, may help find gliomas and may help in planning surgery.
Primary Outcome
To determine the optimal PET threshold for distinguishing HGG from LGG brain tissue, receiver operating characteristic (ROC) analysis and the Youden's index (sum of the sensitivity and specificity - 1) will be used. The Youden's index will be calculated for each possible T/N threshold. The final ROC area under the curve (AUC) value and confidence intervals will be estimated using ROC analysis methods for clustered continuous data as described by Obychowski.
Interventions
- PROCEDURE Computed Tomography
- PROCEDURE Biopsy
- OTHER Laboratory Biomarker Analysis
- PROCEDURE Diffusion Weighted Imaging
- DRUG Fluorine F 18 Fluorodopa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2014-01-22 |
| Est. Completion | 2024-01-10 |
| Phase | Early Phase 1 |
What the finished NCT02020720 record still lists
NCT02020720 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (36% higher).
The record links to 0 conditions, and to 5 interventions - of which Computed Tomography is the first listed.
NCT02020720 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02020720 about?
NCT02020720 is a clinical study titled "18F-DOPA-PET in Planning Surgery in Patients With Gliomas". This pilot clinical trial studies fluorine F 18 fluorodopa (18F-DOPA)-positron emission tomography (PET) in planning surgery in patients with gliomas. New imaging procedures, such as 18F-DOPA-PET scan, may help find gliomas and may help in planning surgery.
What is the current status of trial NCT02020720?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 72 participants. The study started on 2014-01-22. Estimated completion is 2024-01-10.
What interventions are being tested in trial NCT02020720?
The interventions under investigation include: Computed Tomography (PROCEDURE), Biopsy (PROCEDURE), Laboratory Biomarker Analysis (OTHER), Diffusion Weighted Imaging (PROCEDURE), Fluorine F 18 Fluorodopa (DRUG).
Who is sponsoring clinical trial NCT02020720?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02020720's enrollment target sits among peer trials
72 319th of 2000 higher than 1,674 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02359253 · 72 participants · NA
Robot Aided Rehabilitation - Intervention
- NCT02962661 · 72 participants · Phase 1
Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
- NCT03113643 · 72 participants · Phase 1
SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
- NCT03187535 · 72 participants · NA
Effect of TEAS on PONV After Spinal Surgery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI