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NCT02020031 · ClinicalTrials.gov registry record · Phase 2
Regional Prophylactic Vancomycin in Revision Total Knee Replacement
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 22
- Enrollment target
NCT02020031: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT02020031 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 22 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02020031, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 22 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (the knee joint) is more effective at preventing infection than the current standard dose which is given intravenously (IV) through a wrist vein.
Primary Outcome
During the procedure, subcutaneous fat samples (approximately 0.5 cm\^3) were taken at regular intervals until skin closure. Vancomycin concentrations were determined by liquid chromatography coupled with tandem mass spectrometry. Times are given as minutes post surgical incision.
Interventions
- DRUG Vancomycin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2013-12 |
| Est. Completion | 2015-06 |
| Phase | Phase 2 |
What the finished NCT02020031 record still lists
NCT02020031 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which Vancomycin is the first listed.
NCT02020031 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02020031 about?
NCT02020031 is a clinical study titled "Regional Prophylactic Vancomycin in Revision Total Knee Replacement". The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (the knee joint) is more effective at preventing infection than the current standard dose which is given intravenously (IV) through a wrist vein.
What is the current status of trial NCT02020031?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2013-12. Estimated completion is 2015-06.
What interventions are being tested in trial NCT02020031?
The interventions under investigation include: Vancomycin (DRUG).
Who is sponsoring clinical trial NCT02020031?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02020031's enrollment target sits among peer trials
22 1790th of 2000 higher than 207 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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