Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 38 of 57

COMPLETED NA

Reducing CVD Risk in African Americans Faith Communities

NCT02235896

COMPLETED

DUCATS Trial: Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel Syndrome

NCT02219555

COMPLETED Phase 4

Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular

NCT02242201

COMPLETED

New Technologies to Determine Carotid Plaque Vulnerability

NCT02224339

COMPLETED

Biomarkers for Intestinal Permeability in Patients With Constipation

NCT02246647

COMPLETED NA

Use of Decision Aids in Clinical Encounters

NCT02136199

COMPLETED Phase 2

Ketamine for Depression and Suicide Risk

NCT02094898

COMPLETED

Probe-based Volumetric Laser Endomicroscopy (pVLE) of Endoscopic Mucosal Resection (EMR) Tissue in Patients With Barrett's Dysplasia

NCT02366039

COMPLETED Phase 1

Role Of Phosphorus And FGF 23 In Patients With Dent Disease

NCT02016235

COMPLETED NA

Safety of Spine Radiofrequency Procedures

NCT02210052

TERMINATED NA

Esophageal Absorption in EoE

NCT02314455

TERMINATED Phase 2

Effect of Ranolazine on Gastrointestinal Motor Function and Pain in Patients With IBS-D

NCT02239926

COMPLETED

Glutamate Probes in Adolescent Depression

NCT02307617

COMPLETED Phase 4

Comparison of Bacteriostatic Saline to Buffered Lidocaine for Ultrasound Guided Hip Joint Injection Local Anesthesia

NCT02209272

COMPLETED NA

Does Cricoid Pressure Reduce the Risk of Aspiration?

NCT02058004

COMPLETED NA

Cryo Balloon for Residual Barrett's Esophagus

NCT02230410

COMPLETED

A Study to Isolate and Test Circulating Tumor Cells Using the ClearCell® FX EP+ System

NCT02370303

COMPLETED Phase 1

Study of Sc-FOS for Pouchitis Prevention

NCT02203955

COMPLETED NA

Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis

NCT02227836

COMPLETED NA

Understanding the Relationship Between Inflammation and Insulin Resistance in the Adipose Tissue

NCT02378077

COMPLETED

Nonlinear Elasticity Mapping of Breast Masses

NCT04863443

COMPLETED Phase 1

Mesenchymal Stem Cell Therapy for Lung Rejection

NCT02181712

COMPLETED

Minimally Invasive Biomarker for Asthma Disease Severity

NCT02225678

COMPLETED Phase 1

High Frequency Oscillations in Neurologic Disease

NCT02235792

COMPLETED Phase 4

Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)

NCT02223364

TERMINATED Phase 1

Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition

NCT02227329

COMPLETED NA

Pilot Study of Between Visit Interaction to Improve Glycemic Control in Pregnancy With Pre-existing Diabetes

NCT02315274

COMPLETED NA

Serum-Derived Bovine Immunoglobulin /Protein Isolate (SBI) 5.0 g Bid on Nutritional Status in Subjects With IBS-D

NCT02163213

COMPLETED Phase 1

Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine

NCT02131545

COMPLETED Phase 4

Effect of Exenatide in Obese Patients With Accelerated Gastric Emptying

NCT02160990

COMPLETED

Development and Assessment of The Polycystic Liver Disease Questionnaire (PLD-Q).

NCT02173080

COMPLETED NA

Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees

NCT02240186

COMPLETED

Early Screen for Discharge Planning in Community Hospitals

NCT02117804

COMPLETED NA

Behavioral Interventions to Prevent or Delay Dementia

NCT02265757

COMPLETED Phase 3

Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management

NCT02129608

COMPLETED Phase 2

Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus

NCT02170870

COMPLETED Phase 1

Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer

NCT01737502

COMPLETED NA

Comparison of Different Oral Rehydration Solutions

NCT02142582

COMPLETED Phase 1

A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

NCT02128581

COMPLETED Phase 1

Azacitidine and Sonidegib or Decitabine in Treating Patients With Myeloid Malignancies

NCT02129101

COMPLETED NA

Community Intervention to Reduce Tobacco Use in Pregnant Women

NCT02083081

TERMINATED NA

PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

NCT02282423

COMPLETED NA

Blood Volume and Hemodynamic Analysis in Patients With Chronic Heart Failure

NCT02120014

COMPLETED Early Phase 1

Vaccine Therapy for Patients With Stage IIIC-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

NCT02111941

TERMINATED Phase 2

Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy

NCT02062632

COMPLETED NA

Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure

NCT02145351

COMPLETED NA

Dignity Therapy/Life Plan in Patients With Pancreatic or Advanced Lung Cancer

NCT02132325

COMPLETED NA

Shared Decision Making in Parents of Children With Head Trauma: Head CT Choice

NCT02063087

COMPLETED Phase 2

Mindfulness-Based Intervention in Breast Cancer Patients Undergoing Chemotherapy

NCT02067351

COMPLETED Phase 2

Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

NCT02123511

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.