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NCT06745882 · ClinicalTrials.gov registry record · Phase 2

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

A Phase 2 study of Non-Small Cell Lung Cancer, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Recruiting
Registry status
Phase 2
Development phase
318
Enrollment target
4
Study locations

NCT06745882 is a Phase 2 study of Non-Small Cell Lung Cancer that is actively recruiting participants, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 318 participants, below the 658-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (52% lower). The trial reports 4 study locations across 3 states.

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The verdict

NCT06745882, a Phase 2 study of Non-Small Cell Lung Cancer, is actively recruiting participants, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

RECRUITING
Registry status
Phase 2
Development phase
318 participants
Enrollment target
4
Study locations

Study Summary

This is a non-registrational, cohort study enrolling eligible Black patients diagnosed with histologically or cytologically, advanced/metastatic NSCLC without known EGFR/ALK/ROS1 tumor mutations, and who are ≥ 18 years of age, ECOG performance status 0-2, and may have detectable ctDNA at baseline.

Conditions Studied

Interventions

  • DRUG Pembrolizumab
  • DRUG Carboplatin
  • DRUG Cisplatin
  • DRUG Pemetrexed
  • DRUG Abraxane

Study Locations (4)

Maryland

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center - Baltimore
  • TidalHealth Peninsula Regional - Salisbury

Florida

  • Moffitt Cancer Center - Tampa

Tennessee

  • Baptist Clinical Research Institute - Memphis

Trial Details

FieldValue
Enrollment Target 318 participants
Start Date 2025-06-13
Est. Completion 2030-01
Phase Phase 2

What the Registry Record Tells You About NCT06745882

The ClinicalTrials.gov registry entry for NCT06745882 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 318 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 658-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (52% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 5 interventions - of which Pembrolizumab is the first listed.

NCT06745882 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Maryland, Florida, Tennessee.

Frequently Asked Questions

What is clinical trial NCT06745882 about?

NCT06745882 is a clinical study titled "Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC". This is a non-registrational, cohort study enrolling eligible Black patients diagnosed with histologically or cytologically, advanced/metastatic NSCLC without known EGFR/ALK/ROS1 tumor mutations, and who are ≥ 18 years of age, ECOG performance status 0-2, and may have detectable ctDNA at baseline.

What is the current status of trial NCT06745882?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 318 participants. The study started on 2025-06-13. Estimated completion is 2030-01.

What conditions does trial NCT06745882 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.

What interventions are being tested in trial NCT06745882?

The interventions under investigation include: Pembrolizumab (DRUG), Carboplatin (DRUG), Cisplatin (DRUG), Pemetrexed (DRUG), Abraxane (DRUG).

Who is sponsoring clinical trial NCT06745882?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06745882 being conducted?

This trial has 4 study locations across Florida, Maryland, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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