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NCT06701812 · ClinicalTrials.gov registry record · Phase 2

Digoxin Medulloblastoma Study

A Phase 2 study of Medulloblastoma and Medulloblastoma, Non-WNT/Non-SHH, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Recruiting
Registry status
Phase 2
Development phase
23
Enrollment target
15
Study locations

NCT06701812: Recruiting Phase 2 study of Medulloblastoma and Medulloblastoma, Non-WNT/Non-SHH, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

NCT06701812 is a Phase 2 study of Medulloblastoma and Medulloblastoma, Non-WNT/Non-SHH that is actively recruiting participants, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 23 participants, below the 140-participant average among 29 other Medulloblastoma trials with a reported enrollment target (84% lower). The trial reports 15 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06701812, a Phase 2 study of Medulloblastoma and Medulloblastoma, Non-WNT/Non-SHH, is actively recruiting participants, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

RECRUITING
Registry status
Phase 2
Development phase
23 participants
Enrollment target
15
Study locations

Study Summary

The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

Primary Outcome

Proportion of patients with progression free survival at 4 months after initiation of treatment.

Interventions

  • DRUG Digoxin

Study Locations (15)

Florida

  • Nemours Jacksonville - Jacksonville
  • University of Miami - Miami
  • Johns Hopkins All Children's - St. Petersburg
  • St. Joseph's Children's Hospital - Tampa

North Carolina

  • UNC Lineberger Comprehensive Cancer Center - Chapel Hill
  • Levine Cancer Institute - Charlotte

Alabama

  • University of Alabama at Birmingham Children's of Alabama - Birmingham

Arkansas

  • Arkansas Childrens Hospital - Little Rock

Connecticut

  • Connecticut Children's Medical Center - Hartford

District of Columbia

  • Children's National Medical Center - Washington D.C.

Maryland

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center - Baltimore

Missouri

  • Washington University St. Louis - St Louis

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2026-01-15
Est. Completion 2027-02
Phase Phase 2

What NCT06701812 shows while recruiting

NCT06701812 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 140-participant average among 29 other Medulloblastoma trials with a reported enrollment target (84% lower).

The record links to 2 conditions, with Medulloblastoma appearing as the primary indexed condition, and to 1 intervention - of which Digoxin is the first listed.

NCT06701812 lists 15 locations in 11 states (Florida, North Carolina, Alabama).

Frequently Asked Questions

What is clinical trial NCT06701812 about?

NCT06701812 is a clinical study titled "Digoxin Medulloblastoma Study". The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

What is the current status of trial NCT06701812?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2026-01-15. Estimated completion is 2027-02.

What conditions does trial NCT06701812 study?

This clinical trial studies the following conditions: Medulloblastoma, Medulloblastoma, Non-WNT/Non-SHH.

What interventions are being tested in trial NCT06701812?

The interventions under investigation include: Digoxin (DRUG).

Who is sponsoring clinical trial NCT06701812?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06701812 being conducted?

This trial has 15 study locations across Alabama, Arkansas, Connecticut, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Medulloblastoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06701812's enrollment target sits among peer trials

23 22nd of 29 higher than 8 of 29 other Medulloblastoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Medulloblastoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06701812, the US trial registry maintained by the National Library of Medicine. NCT06701812 (small enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.