Edwards Lifesciences
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, Edwards Lifesciences sits in the top decile of US sponsors by registered trial count (#343 of 15,742 sponsors by registered trial count).
Edwards Lifesciences: 57 sponsored US clinical trials, 10 recruiting.
Edwards Lifesciences sponsors 57 registered US clinical trials on ClinicalTrials.gov, 10 of them currently recruiting, and 22 completed. The most-studied condition in this pipeline is Heart Failure, with 5 trials.
Top-decile sponsor footprint
Edwards Lifesciences ranks in the top decile of sponsors by registered trial count (#343 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
22 of 25 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
57 total, page 1 of 2
HemoSphere Alta Study
NCT07148323
TTVR STRONG Under Coverage With Evidence Development (CED) Study
NCT06833476
Personal BP - CAI Study
NCT06492746
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
NCT05172973
TVMR With the INNOVALVE System Trial - Early Feasibility Study
NCT04919980
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
NCT04889872
The ENCIRCLE Trial
NCT04153292
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
NCT04097145
PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
NCT02744677
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System
NCT05686317
Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve
NCT05526560
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
NCT05172960
ALTERRA Post-Approval Study
NCT05378386
HPI (Hypotension Prediction Index) Care Trial
NCT05083403
COMPASSION S3 Post-Approval Study
NCT04860765
TRISCEND II Pivotal Trial
NCT04482062
Beating Heart Mitral Valve Repair With the HARPOON™ System
NCT04375332
2019-06 TRISCEND Study
NCT04221490
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial
NCT03706833
ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
NCT03517436
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
NCT03523416
Clinical Study of Edwards Cardioband FIT Valve Repair System
NCT03382457
PARTNER 3 Trial - Mitral Valve in Valve
NCT03193801
SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation
NCT03230747
ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent
NCT03130777
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
NCT03042104
PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
NCT02675114
Edwards EVOQUE Eos MISCEND Study
NCT02718001
ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)
NCT01757665
TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)
NCT07684313
Autus Valve Continued Access Study (CAS)
NCT07466745
Hypotension Prediction Index (HPI) SMART-BP Trial
NCT05105477
HUDDLE: Heart Health: Understanding & Diagnosing Disease by Leveraging Echocardiograms
NCT05009589
Pediatric Cardiac Output Monitoring Observational Study
NCT04465370
Hypotension Prediction Index Study (HPI Study)
NCT03805217
Edwards CLASP TR EFS
NCT03745313
RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65
NCT03680040
Assisted Fluid Management IDE Study
NCT03469570
COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction
NCT02987387
The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study
NCT03170349
Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)
NCT03016975
COMMENCE Pulmonary: Clinical Evaluation of Edwards Pericardial Aortic Bioprosthesis (Model 11000A) for Pulmonary Valve Replacement
NCT02656290
Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System
NCT02471807
PARTNER II Trial: S3iCAP
NCT02687035
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - S3 Intermediate
NCT03222128
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7
NCT03222141
Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve
NCT01700439
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve
NCT03225001
The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII B
NCT02184442
What is open in the Edwards Lifesciences pipeline
10 recruiting of 57 indexed (18% open); 22 completed (39%).
Phase labels are sparse on this sponsor index, so phase mix is not charted here.
Top condition: Heart Failure (5 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Edwards Lifesciences: open-pipeline peers nationwide
Peers matched on 57 registered trials and 18% open enrollment, not the therapeutic-area sidebar.
Edwards Lifesciences sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 57 trials (± recruiting share)
- St. Luke's-Roosevelt Hospital Center · 57 trials · 0% recruiting
- Supernus Pharmaceuticals · 57 trials · 11% recruiting
- USDA Grand Forks Human Nutrition Research Center · 57 trials · 4% recruiting
- East Carolina University · 58 trials · 12% recruiting
Sponsors near 18% open enrollment (± trial volume)
- Indiana University · 18% recruiting · 890 trials
- University of California, Los Angeles · 18% recruiting · 897 trials
- University of South Florida · 17% recruiting · 252 trials
- VA Office of Research and Development · 17% recruiting · 1,668 trials
Related
What to do with this Edwards Lifesciences page
57 registered trials is a research-attention snapshot, not an endorsement of Edwards Lifesciences or any single study.
- 10 of Edwards Lifesciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Heart Failure is the condition Edwards Lifesciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Heart Failure trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Edwards Lifesciences pipeline card: 57 registered trials from official public datasets.Report a data error.