Edwards Lifesciences
Trial Pipeline
HemoSphere Alta Study
NCT07148323
TTVR STRONG Under Coverage With Evidence Development (CED) Study
NCT06833476
Personal BP - CAI Study
NCT06492746
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
NCT05172973
TVMR With the INNOVALVE System Trial - Early Feasibility Study
NCT04919980
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
NCT04889872
The ENCIRCLE Trial
NCT04153292
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
NCT04097145
PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
NCT02744677
ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System
NCT05686317
Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve
NCT05526560
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
NCT05172960
ALTERRA Post-Approval Study
NCT05378386
HPI (Hypotension Prediction Index) Care Trial
NCT05083403
COMPASSION S3 Post-Approval Study
NCT04860765
TRISCEND II Pivotal Trial
NCT04482062
Beating Heart Mitral Valve Repair With the HARPOON™ System
NCT04375332
2019-06 TRISCEND Study
NCT04221490
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial
NCT03706833
ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
NCT03517436
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
NCT03523416
Clinical Study of Edwards Cardioband FIT Valve Repair System
NCT03382457
PARTNER 3 Trial - Mitral Valve in Valve
NCT03193801
SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation
NCT03230747
ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent
NCT03130777
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
NCT03042104
PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
NCT02675114
Edwards EVOQUE Eos MISCEND Study
NCT02718001
ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)
NCT01757665
HUDDLE: Heart Health: Understanding & Diagnosing Disease by Leveraging Echocardiograms
NCT05009589
PARTNER II Trial: S3iCAP
NCT02687035
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - S3 Intermediate
NCT03222128
Clinical Study of the Intravenous Blood Glucose System in Hospitalized Adult Elective or Non-Emergent Surgery and Medical/Surgical Intensive Care Unit Patients
NCT00906490
What the Pipeline for Edwards Lifesciences Shows
According to the ClinicalTrials.gov registry, Edwards Lifesciences is linked to 34 US clinical trials across every stage of research activity. Of those, 10 studies are currently recruiting — about 29% of the sponsor's indexed portfolio — and 4 are already marked complete, representing roughly 12% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Edwards Lifesciences reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Edwards Lifesciences is Heart Failure with 5 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.