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NCT02744677 · ClinicalTrials.gov registry record · NA

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

A NA study of Complex Congenital Heart Defect and Pulmonary Valve Insufficiency, sponsored by Edwards Lifesciences.

Recruiting
Registry status
NA
Development phase
108
Enrollment target
20
Study locations

NCT02744677 is a NA study of Complex Congenital Heart Defect and Pulmonary Valve Insufficiency that is actively recruiting participants, run by Edwards Lifesciences. The registered enrollment target is 108 participants, roughly in line with the 115-participant average among 3 other Complex Congenital Heart Defect trials with a reported enrollment target. The trial reports 20 study locations across 14 states.

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The verdict

NCT02744677, a NA study of Complex Congenital Heart Defect and Pulmonary Valve Insufficiency, is actively recruiting participants, sponsored by Edwards Lifesciences.

RECRUITING
Registry status
NA
Development phase
108 participants
Enrollment target
20
Study locations

Study Summary

This study will demonstrate the safety and effectiveness of the Edwards Lifesciences SAPIEN 3/SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve (THV) Systems in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted valve in the pulmonic position with a clinical indication for intervention.

Interventions

  • DEVICE SAPIEN 3/SAPIEN 3 Ultra RESILIA THV
  • DEVICE SAPIEN 3 THV
  • DEVICE SAPIEN 3 Ultra RESILIA THV

Study Locations (20)

Ohio

  • The Lindner Research Center at Christ Hospital - Cincinnati
  • Cincinnati Children's Hospital - Cincinnati
  • Nationwide Children's Hospital - Columbus

California

  • University of California, Los Angeles - Los Angeles
  • University of California,, San Francisco (UCSF) - San Francisco

Massachusetts

  • Massachusetts General Hospital - Boston
  • Boston Children's Hospital - Boston

Missouri

  • St. Louis Children's Hospital - St Louis
  • Washington University Barnes- Jewish Medical/ St. Louis Children's Hospital - St Louis

Pennsylvania

  • Penn Presbyterian Medical Center, University of Pennsylvania/ Children's Hospital of Philadelphia - Philadelphia
  • UPMC Children's Hospital of Pittsburgh - Pittsburgh

Arkansas

  • Arkansas Children's Hospital - Little Rock

Colorado

  • Childrens Hospital of Colorado - Aurora

Georgia

  • Emory University/Children's Healthcare of Atlanta - Atlanta

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2016-07-05
Est. Completion 2031-06
Phase NA

Sponsor

Edwards Lifesciences

57 total trials

What the Registry Record Tells You About NCT02744677

The ClinicalTrials.gov registry entry for NCT02744677 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 115-participant average among 3 other Complex Congenital Heart Defect trials with a reported enrollment target. The listed sponsor is Edwards Lifesciences, which has 57 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Complex Congenital Heart Defect appearing as the primary indexed condition, and to 3 interventions - of which SAPIEN 3/SAPIEN 3 Ultra RESILIA THV is the first listed.

NCT02744677 reports 20 study locations spanning 14 distinct geographic areas - top geographies include Ohio, California, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT02744677 about?

NCT02744677 is a clinical study titled "COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction". This study will demonstrate the safety and effectiveness of the Edwards Lifesciences SAPIEN 3/SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve (THV) Systems in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted valve in the pulmonic position with a c...

What is the current status of trial NCT02744677?

This trial is currently recruiting. It is a NA study. The enrollment target is 108 participants. The study started on 2016-07-05. Estimated completion is 2031-06.

What conditions does trial NCT02744677 study?

This clinical trial studies the following conditions: Complex Congenital Heart Defect, Pulmonary Valve Insufficiency, Dysfunctional RVOT Conduit, Pulmonary Valve Degeneration.

What interventions are being tested in trial NCT02744677?

The interventions under investigation include: SAPIEN 3/SAPIEN 3 Ultra RESILIA THV (DEVICE), SAPIEN 3 THV (DEVICE), SAPIEN 3 Ultra RESILIA THV (DEVICE).

Who is sponsoring clinical trial NCT02744677?

This trial is sponsored by Edwards Lifesciences, which has 57 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02744677 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, Georgia, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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