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NCT03042104 · ClinicalTrials.gov registry record · NA

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis

A NA study of Heart Diseases and Aortic Stenosis, Severe, sponsored by Edwards Lifesciences.

Active
Registry status
NA
Development phase
901
Enrollment target
20
Study locations

NCT03042104 is a NA study of Heart Diseases and Aortic Stenosis, Severe that is active but no longer recruiting, run by Edwards Lifesciences. The registered enrollment target is 901 participants, below the 5,522-participant average among 85 other Heart Diseases trials with a reported enrollment target (84% lower). The trial reports 20 study locations across 8 states.

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The verdict

NCT03042104, a NA study of Heart Diseases and Aortic Stenosis, Severe, is active but no longer recruiting, sponsored by Edwards Lifesciences.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
901 participants
Enrollment target
20
Study locations

Study Summary

This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis.

Interventions

  • DEVICE Edwards SAPIEN 3 / SAPIEN 3 Ultra THV

Study Locations (20)

California

  • Mills Peninsula Health Services - Burlingame
  • Cedars-Sinai Medical Center - Los Angeles
  • Hoag Memorial Hospital Presbyterian - Newport Beach
  • Huntington Hospital - Pasadena
  • UC Davis Medical Center - Sacramento
  • Kaiser San Francisco Medical Center - San Francisco
  • Stanford Hospital and Clinics Palo Alto - Stanford

Illinois

  • Northwestern University - Chicago
  • Rush University Medical Center Chicago - Chicago
  • NorthShore University HealthSystem Research Institution - Evanston
  • Alexian Brothers Hospital Network - Lisle
  • Prairie Education and Research Cooperative - Springfield

Florida

  • The Cardiac & Vascular Institute Research Foundation - Gainesville
  • University of Florida - Gainesville

Georgia

  • Piedmont Heart Institute - Atlanta
  • Emory University - Atlanta

Arizona

  • Banner University Medical Center - Phoenix

Colorado

  • UC Health Northern Colorado (Medical Center of the Rockies) - Loveland

Connecticut

  • Yale University - New Haven

District of Columbia

  • Washington Hospital Center DC - Washington D.C.

Trial Details

FieldValue
Enrollment Target 901 participants
Start Date 2017-07-12
Est. Completion 2032-03
Phase NA

Sponsor

Edwards Lifesciences

57 total trials

What the Registry Record Tells You About NCT03042104

The ClinicalTrials.gov registry entry for NCT03042104 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 901 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,522-participant average among 85 other Heart Diseases trials with a reported enrollment target (84% lower). The listed sponsor is Edwards Lifesciences, which has 57 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Heart Diseases appearing as the primary indexed condition, and to 1 intervention - of which Edwards SAPIEN 3 / SAPIEN 3 Ultra THV is the first listed.

NCT03042104 reports 20 study locations spanning 8 distinct geographic areas - top geographies include California, Illinois, Florida.

Frequently Asked Questions

What is clinical trial NCT03042104 about?

NCT03042104 is a clinical study titled "EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis". This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical surveillance (CS) in asymptomatic patients with severe, calcific aortic stenosis.

What is the current status of trial NCT03042104?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 901 participants. The study started on 2017-07-12. Estimated completion is 2032-03.

What conditions does trial NCT03042104 study?

This clinical trial studies the following conditions: Heart Diseases, Aortic Stenosis, Severe.

What interventions are being tested in trial NCT03042104?

The interventions under investigation include: Edwards SAPIEN 3 / SAPIEN 3 Ultra THV (DEVICE).

Who is sponsoring clinical trial NCT03042104?

This trial is sponsored by Edwards Lifesciences, which has 57 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03042104 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.