Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 13 recruiting now official registry

Tricuspid Regurgitation clinical trials

13 of 18 indexed Tricuspid Regurgitation trials are currently recruiting.

18 US clinical trials · 13 currently recruiting

Tricuspid Regurgitation is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. The most active sponsor is Edwards Lifesciences, running 3 of these trials.

The research picture

Tricuspid Regurgitation has 18 registered US clinical trials, 13 of them open to new participants right now, about 72% of the total.

13
recruiting participants now
72%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
3
top sponsor: Edwards Lifesciences

Active & Recent Trials

18 total, page 1 of 1

RECRUITING 2,200 participants

TriClip CED RWE Study

Abbott Medical Devices

NCT06920745

RECRUITING 2,044 participants

TTVR STRONG Under Coverage With Evidence Development (CED) Study

Edwards Lifesciences

NCT06833476

RECRUITING NA 870 participants

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Edwards Lifesciences

NCT04097145

RECRUITING 800 participants

Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment

Montefiore Medical Center

NCT06033274

RECRUITING 550 participants

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

Abbott Medical Devices

NCT04761120

RECRUITING NA 150 participants

TTVR Early Feasibility Study

Medtronic Cardiovascular

NCT04433065

RECRUITING NA 50 participants

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

P+F Products + Features USA

NCT06137807

RECRUITING NA 45 participants

Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

Laplace Interventional

NCT06183684

RECRUITING NA 40 participants

Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD Patients

University of Washington

NCT02537769

RECRUITING NA 30 participants

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

VDyne

NCT05848284

RECRUITING NA 30 participants

Trisol System EFS Study

Trisol Medical

NCT04905017

RECRUITING NA 15 participants

EFS of the DUO System for Tricuspid Regurgitation

CroiValve Limited

NCT05913908

RECRUITING NA 15 participants

Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)

Innoventric

NCT06212193

ACTIVE NOT RECRUITING NA 572 participants

TRILUMINATE Pivotal Trial

Abbott Medical Devices

NCT03904147

ACTIVE NOT RECRUITING NA 75 participants

Clinical Study of Edwards Cardioband FIT Valve Repair System

Edwards Lifesciences

NCT03382457

COMPLETED 1,145 participants

Development of an Algorithm to Differentiate Heart Murmurs Using Electronic Stethoscopes

Eko Devices

NCT04400513

COMPLETED NA 401 participants

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Icahn School of Medicine at Mount Sinai

NCT02675244

COMPLETED NA 75 participants

Staging Classification of Severe Tricuspid Regurgitation Using Novel Cardiac Imaging Techniques

Mayo Clinic

NCT05006443

Phase Distribution

Phase data not available

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Tricuspid Regurgitation Trial Landscape

18 indexed Tricuspid Regurgitation studies · 13 recruiting (72%).

Phase mix: 0 late (III/IV) vs 0 early (I/II).

Top sponsor: Edwards Lifesciences (3 trials), 9 others listed. 18 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Tricuspid Regurgitation?

PlainTrial tracks 18 US clinical trials for Tricuspid Regurgitation, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Tricuspid Regurgitation?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.