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NCT03222141 · ClinicalTrials.gov registry record · NA

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7

A NA study, sponsored by Edwards Lifesciences.

Completed
Registry status
NA
Development phase
583
Enrollment target

NCT03222141: Completed NA study, sponsored by Edwards Lifesciences.

NCT03222141 is a NA study that has completed, run by Edwards Lifesciences. The registered enrollment target is 583 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03222141, a NA study, has completed, sponsored by Edwards Lifesciences.

COMPLETED
Registry status
NA
Development phase
583 participants
Enrollment target

Study Summary

The purpose of this trial is to determine the safety and effectiveness of the Edwards SAPIEN 3 transcatheter heart valve and delivery systems which are intended for use in patients with symptomatic, calcific, severe aortic stenosis, and are in high risk.

Primary Outcome

The composite rate of all-cause mortality, all stroke, and AI ≥ moderate for patients deemed as 'high risk' using the Edwards SAPIEN 3 transcatheter heart valve (THV).

Interventions

  • DEVICE TAVR Implantation of the THV Prosthesis

Trial Details

FieldValue
Enrollment Target 583 participants
Start Date 2013-10
Est. Completion 2020-08
Phase NA
Edwards Lifesciences

57 total trials

What the finished NCT03222141 record still lists

NCT03222141 is an interventional study that assigns participants to a tested intervention. The registered 583 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 1 intervention - of which TAVR Implantation of the THV Prosthesis is the first listed.

NCT03222141 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03222141 about?

NCT03222141 is a clinical study titled "PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - High Risk and Nested Registry 7". The purpose of this trial is to determine the safety and effectiveness of the Edwards SAPIEN 3 transcatheter heart valve and delivery systems which are intended for use in patients with symptomatic, calcific, severe aortic stenosis, and are in high risk.

What is the current status of trial NCT03222141?

This trial is currently completed. It is a NA study. The enrollment target is 583 participants. The study started on 2013-10. Estimated completion is 2020-08.

What interventions are being tested in trial NCT03222141?

The interventions under investigation include: TAVR Implantation of the THV Prosthesis (DEVICE).

Who is sponsoring clinical trial NCT03222141?

This trial is sponsored by Edwards Lifesciences, which has 57 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03222141's enrollment target sits among peer trials

583 177th of 2000 higher than 1,824 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03222141, the US trial registry maintained by the National Library of Medicine. NCT03222141 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.