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NCT04860765 · ClinicalTrials.gov registry record

COMPASSION S3 Post-Approval Study

A clinical trial of Complex Congenital Heart Defect and Pulmonary Valve Insufficiency, sponsored by Edwards Lifesciences.

Active
Registry status
150
Enrollment target
19
Study locations

NCT04860765 is a study of Complex Congenital Heart Defect and Pulmonary Valve Insufficiency that is active but no longer recruiting, run by Edwards Lifesciences. The registered enrollment target is 150 participants, above the 101-participant average among 3 other Complex Congenital Heart Defect trials with a reported enrollment target (49% higher). The trial reports 19 study locations across 15 states.

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The verdict

NCT04860765, a study of Complex Congenital Heart Defect and Pulmonary Valve Insufficiency, is active but no longer recruiting, sponsored by Edwards Lifesciences.

ACTIVE NOT RECRUITING
Registry status
150 participants
Enrollment target
19
Study locations

Study Summary

This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve in the pulmonic position with a clinical indication for intervention.

Interventions

  • DEVICE SAPIEN 3 THV

Study Locations (19)

New York

  • Mount Sinai - New York
  • Columbia University Medical Center/NYPH - New York

Ohio

  • Cincinatti Children's Hospital - Cincinnati
  • Nationwide Children's Hospital - Columbus

Pennsylvania

  • Children's Hospital of Philadelphia - Philadelphia
  • University of Pittsburgh Medical Center - Pittsburgh

Texas

  • Dell Children's - Austin
  • Children's Health Dallas - Dallas

Alabama

  • University of Alabama - Birmingham

California

  • Cedars Sinai - Los Angeles

Colorado

  • Children's Hospital of Colorado - Aurora

Illinois

  • Advocate Childrens Hospital - Oak Lawn

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2021-04-13
Est. Completion 2030-08

Sponsor

Edwards Lifesciences

57 total trials

What the Registry Record Tells You About NCT04860765

The ClinicalTrials.gov registry entry for NCT04860765 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 101-participant average among 3 other Complex Congenital Heart Defect trials with a reported enrollment target (49% higher). The listed sponsor is Edwards Lifesciences, which has 57 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Complex Congenital Heart Defect appearing as the primary indexed condition, and to 1 intervention - of which SAPIEN 3 THV is the first listed.

NCT04860765 reports 19 study locations spanning 15 distinct geographic areas - top geographies include New York, Ohio, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04860765 about?

NCT04860765 is a clinical study titled "COMPASSION S3 Post-Approval Study". This study will monitor device performance and outcomes of the SAPIEN 3 Transcatheter Heart Valve (THV) System in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted surgical valve in the pulmonic position with a clinical indication for intervention.

What is the current status of trial NCT04860765?

This trial is currently active not recruiting. The enrollment target is 150 participants. The study started on 2021-04-13. Estimated completion is 2030-08.

What conditions does trial NCT04860765 study?

This clinical trial studies the following conditions: Complex Congenital Heart Defect, Pulmonary Valve Insufficiency, Dysfunctional RVOT Conduit, Pulmonary Valve Degeneration, Pulmonary Valve; Obstruction.

What interventions are being tested in trial NCT04860765?

The interventions under investigation include: SAPIEN 3 THV (DEVICE).

Who is sponsoring clinical trial NCT04860765?

This trial is sponsored by Edwards Lifesciences, which has 57 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04860765 being conducted?

This trial has 19 study locations across Alabama, California, Colorado, Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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