Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 6 of 35

NOT YET RECRUITING NA

Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD

NCT07227987

NOT YET RECRUITING NA

Lattice Radiotherapy for Adults With Large Tumors

NCT07647679

NOT YET RECRUITING Phase 2

Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma

NCT07603375

NOT YET RECRUITING Phase 4

IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency

NCT07686692

NOT YET RECRUITING Phase 1

A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia

NCT06327373

NOT YET RECRUITING Phase 1

A Widely Inclusive, Hybrid-Decentralized Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS

NCT07589764

NOT YET RECRUITING Phase 3

Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)

NCT06525389

NOT YET RECRUITING Phase 3

PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

NCT07232069

NOT YET RECRUITING NA

Food DNA Digestion

NCT06687226

NOT YET RECRUITING NA

Robotic OCT for ER Anterior Eye Exams

NCT06566339

NOT YET RECRUITING Phase 4

NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings

NCT06854029

NOT YET RECRUITING NA

Pilot Feasibility Study With Doulas

NCT07614789

NOT YET RECRUITING Phase 4

ESP Blocks for Posterior Spinal Fusion

NCT07228039

NOT YET RECRUITING Phase 2

Phosphate in Acute Pancreatitis

NCT07681050

NOT YET RECRUITING Phase 1

Optimizing PreTerm Infant Ampicillin Dosing

NCT07610486

NOT YET RECRUITING NA

Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children

NCT07390773

NOT YET RECRUITING NA

Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment

NCT07685249

NOT YET RECRUITING

GBPDC: Gut-Brain in PD Consortium Master Protocol

NCT07567794

NOT YET RECRUITING NA

Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors

NCT07117695

NOT YET RECRUITING NA

Overnight TI in TLE

NCT07434986

NOT YET RECRUITING NA

Planning Grant for TOPS for Breast Cancer Survivors

NCT06658912

NOT YET RECRUITING NA

Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF

NCT04956978

NOT YET RECRUITING NA

A Study Testing a Digital, Gamified Early Intervention for Eating Disorders ("FlexED")

NCT07632248

NOT YET RECRUITING NA

Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain

NCT06987786

NOT YET RECRUITING Phase 3

Phenobarbital for Agitated Delirium

NCT07548489

NOT YET RECRUITING NA

Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

NCT05459077

NOT YET RECRUITING NA

Spot Compression Ultrasound Compared to Traditional Breast Ultrasound

NCT07471672

NOT YET RECRUITING Phase 1

Studies of Insulin and Glucagon Action in the Liver

NCT07300982

NOT YET RECRUITING

Ultrasound Imaging of the Head, Neck, and Airway

NCT07406061

NOT YET RECRUITING

Duke Virtual IntEgrated Workflow

NCT07406074

NOT YET RECRUITING Phase 4

Tirzepatide in Idiopathic Intracranial Hypertension Trial

NCT07191873

COMPLETED Phase 4

Dispersion Following ESP Versus ITP Blocks Using Lidocaine Study

NCT06843343

COMPLETED NA

Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction

NCT06927973

COMPLETED Phase 1

NASA Prebreathe Study

NCT06740305

COMPLETED NA

Treating Psychosocial Distress in Glaucoma

NCT06053307

COMPLETED NA

Food is Medicine: Pilot Study

NCT06797453

COMPLETED NA

Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE

NCT06720584

COMPLETED NA

LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer

NCT06464562

COMPLETED NA

Addressing Fertility Information Needs and Distress

NCT06834945

COMPLETED NA

Cognitive Training RCT for Older Chinese Americans

NCT05355870

COMPLETED NA

Ultrasound-guided Nerve Block Training Model and Evaluation Method

NCT06219005

COMPLETED NA

A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study

NCT06637358

COMPLETED NA

VitalTraq for the Detection of CRS

NCT06415656

COMPLETED Phase 4

Rectus Sheath Block for Analgesia After Gynecological Laparotomy

NCT06575699

COMPLETED NA

Black Resilient Caregivers

NCT06458790

COMPLETED NA

Ambient Digital Scribes Populating Clinical Notes

NCT06519123

COMPLETED Phase 4

Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study

NCT06503900

COMPLETED Phase 1

Single Dose Texas 2017 (H3N2) Challenge Study

NCT06476275

COMPLETED Phase 4

Immunogenicity of Influenza Vaccinations

NCT06518577

COMPLETED NA

Metronidazole SC Penetrance With Moisturizers

NCT06434519

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.