Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 6 of 35
Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD
NCT07227987
Lattice Radiotherapy for Adults With Large Tumors
NCT07647679
Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma
NCT07603375
IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency
NCT07686692
A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia
NCT06327373
A Widely Inclusive, Hybrid-Decentralized Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS
NCT07589764
Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)
NCT06525389
PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
NCT07232069
Food DNA Digestion
NCT06687226
Robotic OCT for ER Anterior Eye Exams
NCT06566339
NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings
NCT06854029
Pilot Feasibility Study With Doulas
NCT07614789
ESP Blocks for Posterior Spinal Fusion
NCT07228039
Phosphate in Acute Pancreatitis
NCT07681050
Optimizing PreTerm Infant Ampicillin Dosing
NCT07610486
Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children
NCT07390773
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
NCT07685249
GBPDC: Gut-Brain in PD Consortium Master Protocol
NCT07567794
Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors
NCT07117695
Overnight TI in TLE
NCT07434986
Planning Grant for TOPS for Breast Cancer Survivors
NCT06658912
Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF
NCT04956978
A Study Testing a Digital, Gamified Early Intervention for Eating Disorders ("FlexED")
NCT07632248
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
NCT06987786
Phenobarbital for Agitated Delirium
NCT07548489
Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression
NCT05459077
Spot Compression Ultrasound Compared to Traditional Breast Ultrasound
NCT07471672
Studies of Insulin and Glucagon Action in the Liver
NCT07300982
Ultrasound Imaging of the Head, Neck, and Airway
NCT07406061
Duke Virtual IntEgrated Workflow
NCT07406074
Tirzepatide in Idiopathic Intracranial Hypertension Trial
NCT07191873
Dispersion Following ESP Versus ITP Blocks Using Lidocaine Study
NCT06843343
Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction
NCT06927973
NASA Prebreathe Study
NCT06740305
Treating Psychosocial Distress in Glaucoma
NCT06053307
Food is Medicine: Pilot Study
NCT06797453
Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE
NCT06720584
LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer
NCT06464562
Addressing Fertility Information Needs and Distress
NCT06834945
Cognitive Training RCT for Older Chinese Americans
NCT05355870
Ultrasound-guided Nerve Block Training Model and Evaluation Method
NCT06219005
A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study
NCT06637358
VitalTraq for the Detection of CRS
NCT06415656
Rectus Sheath Block for Analgesia After Gynecological Laparotomy
NCT06575699
Black Resilient Caregivers
NCT06458790
Ambient Digital Scribes Populating Clinical Notes
NCT06519123
Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study
NCT06503900
Single Dose Texas 2017 (H3N2) Challenge Study
NCT06476275
Immunogenicity of Influenza Vaccinations
NCT06518577
Metronidazole SC Penetrance With Moisturizers
NCT06434519
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.