Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 6 of 35
Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD
NCT07227987
Lattice Radiotherapy for Adults With Large Tumors
NCT07647679
Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma
NCT07603375
IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency
NCT07686692
A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia
NCT06327373
A Widely Inclusive, Hybrid-Decentralized Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALS
NCT07589764
Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)
NCT06525389
PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
NCT07232069
Food DNA Digestion
NCT06687226
Robotic OCT for ER Anterior Eye Exams
NCT06566339
NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings
NCT06854029
Pilot Feasibility Study With Doulas
NCT07614789
ESP Blocks for Posterior Spinal Fusion
NCT07228039
Phosphate in Acute Pancreatitis
NCT07681050
Optimizing PreTerm Infant Ampicillin Dosing
NCT07610486
Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children
NCT07390773
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
NCT07685249
GBPDC: Gut-Brain in PD Consortium Master Protocol
NCT07567794
Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors
NCT07117695
Overnight TI in TLE
NCT07434986
Planning Grant for TOPS for Breast Cancer Survivors
NCT06658912
Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF
NCT04956978
A Study Testing a Digital, Gamified Early Intervention for Eating Disorders ("FlexED")
NCT07632248
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
NCT06987786
Phenobarbital for Agitated Delirium
NCT07548489
Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression
NCT05459077
Spot Compression Ultrasound Compared to Traditional Breast Ultrasound
NCT07471672
Studies of Insulin and Glucagon Action in the Liver
NCT07300982
Ultrasound Imaging of the Head, Neck, and Airway
NCT07406061
Duke Virtual IntEgrated Workflow
NCT07406074
Tirzepatide in Idiopathic Intracranial Hypertension Trial
NCT07191873
Dispersion Following ESP Versus ITP Blocks Using Lidocaine Study
NCT06843343
Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction
NCT06927973
NASA Prebreathe Study
NCT06740305
Treating Psychosocial Distress in Glaucoma
NCT06053307
Food is Medicine: Pilot Study
NCT06797453
Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE
NCT06720584
LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer
NCT06464562
Addressing Fertility Information Needs and Distress
NCT06834945
Cognitive Training RCT for Older Chinese Americans
NCT05355870
Ultrasound-guided Nerve Block Training Model and Evaluation Method
NCT06219005
A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study
NCT06637358
VitalTraq for the Detection of CRS
NCT06415656
Rectus Sheath Block for Analgesia After Gynecological Laparotomy
NCT06575699
Black Resilient Caregivers
NCT06458790
Ambient Digital Scribes Populating Clinical Notes
NCT06519123
Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study
NCT06503900
Single Dose Texas 2017 (H3N2) Challenge Study
NCT06476275
Immunogenicity of Influenza Vaccinations
NCT06518577
Metronidazole SC Penetrance With Moisturizers
NCT06434519
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.