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NCT06740305 · ClinicalTrials.gov registry record · Phase 1
NASA Prebreathe Study
A Phase 1 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
NCT06740305 is a Phase 1 study that has completed, run by Duke University. The registered enrollment target is 19 participants.
The verdict
NCT06740305, a Phase 1 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
Study Summary
This study will validate the experimental method and chamber facility at the Duke Center for Hyperbaric Medicine \& Environmental Physiology and test team capabilities to support NASA decompression sickness (DCS) studies. This project is related to development of protocols for extravehicular activity (EVA, "spacewalks") to minimize the risk of decompression sickness. Duke will perform four test days, collecting and recording data each day. Each test day will involve 3 volunteer subjects ages 18-50 years, who will breathe 100% oxygen for 6 hours. This will be followed by 6 hours in the hypobaric chamber at 1/3 atmosphere, during which subjects will perform various tasks, including arm and leg exercises, and undergo ultrasound testing to detect vascular bubbles. End-points will include bubble scores, and decompression sickness (DCS). If subjects develop DCS symptoms they will immediately be recompressed to ambient pressure and be assessed and treated.
Interventions
- OTHER Altitude
- DRUG 100% Oxygen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2025-05-05 |
| Est. Completion | 2025-08-21 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06740305
The ClinicalTrials.gov registry entry for NCT06740305 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Altitude is the first listed.
NCT06740305 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06740305 about?
NCT06740305 is a clinical study titled "NASA Prebreathe Study". This study will validate the experimental method and chamber facility at the Duke Center for Hyperbaric Medicine \& Environmental Physiology and test team capabilities to support NASA decompression sickness (DCS) studies. This project is related to development of protocols for extravehicular activit...
What is the current status of trial NCT06740305?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2025-05-05. Estimated completion is 2025-08-21.
What interventions are being tested in trial NCT06740305?
The interventions under investigation include: Altitude (OTHER), 100% Oxygen (DRUG).
Who is sponsoring clinical trial NCT06740305?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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