Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 7 of 35
Integration of Mindfulness and Acupuncture After Spine Surgery
NCT06429072
RECOVER-SLEEP: Platform Protocol
NCT06404086
RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))
NCT06404073
RECOVER-ENERGIZE Platform Protocol
NCT06404047
Project HOPES: Healthy Options for Pain and Ending Smoking. A Program for Cancer Survivors.
NCT06029907
ACT for Infertility: Case Series
NCT06388044
ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments
NCT06429059
Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase
NCT06278883
FlexED: A Digital, Gamified Early Intervention for Eating Disorders
NCT05609409
Family Involvement Hospital Ethnography
NCT06374992
Chlorhexidine Gluconate Bathing Education Video Among Hospitalized Patients
NCT06112626
At-Home Diaphragmatic Interventions for Voiding Abnormalities (DIVA)
NCT06165731
NDPH Biomarker Study in Children and Adolescents
NCT06018025
Pneumonia Direct Pilot
NCT06181669
Comparative Study of High Performance Low-Cost Optical Coherence Tomography
NCT05530460
Food Is Medicine: Makin' Healthy Groceries
NCT06214806
Evaluation of Advanced Imaging and Visualization for Clinical Deep Brain Stimulation
NCT06191874
Preventing Failed Extubations
NCT06301867
Medication Adherence in Rheumatic Diseases
NCT06018350
Pilot Testing of an Equity Focused and Trauma-informed Communication Intervention During Family-centered Rounds
NCT05618652
Strong Hearts: A Remote, App-Enabled, Exercise Program for Patients With Congenital Heart Disease (Strong Hearts App)
NCT05853705
Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain
NCT05940012
Healthy Lifestyles After Cancer for Adolescents and Young Adults: A Program to Reduce Cardiovascular Risk Factors
NCT05869604
Conduction System Pacing With INGEVITY+
NCT06014866
Glioblastoma Psychosocial Support Program
NCT06038604
DHL Survey on Generative AI for MyChart Messaging
NCT06108037
Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children
NCT06038617
El Faro: Addressing Mental Health Inequities Among Latinx Children With ADHD in Durham
NCT05928182
CLARE Mobile App for Caregiver Training and Support
NCT05877586
Emergency Department Re-evaluation Software Pilot Study
NCT05831046
Initial Testing of a Mobile App Pain Coping Intervention for Outpatient Oncology Settings (PainPac)
NCT05686122
Targeted Health Coaching to Improve Physical Activity Post-Structured Cardiac Rehabilitation
NCT05773287
Comparative Immunogenicity of Concomitant vs Sequential mRNA COVID-19 and Influenza Vaccinations
NCT06020118
Improving Physician Vaccine Recommendation Using Social Norms, Trust, and Presumptive Language
NCT05957393
COVID-19 Vaccination Hesitancy in Adults With Sickle Cell Disease
NCT05998824
Real-World Analysis of Belantamab Mafodotin Care Patterns in Patients With Relapsed and/or Refractory Multiple Myeloma
NCT05986682
Improving Detection and Evidence-based Care of NAFLD in Latinx and Black Patients With Type 2 Diabetes
NCT05844137
Directed Topical Drug Delivery for Treatment for PASC Hyposmia
NCT05970731
RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms
NCT05965739
Acute Coronary Syndrome KCMC
NCT04563546
RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms
NCT05965752
Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 2)
NCT05831228
RADx-UP CDCC Rapid Research Pilot Program "Culturally-relevant Community Connections (C3) to Increase COVID-19 Testing
NCT05918952
Personal Resilience Skills to Improve Surgery Training
NCT06139614
CIC Behavioral Economics in Children With Spina Bifida
NCT05562713
Low-Cost, Portable Flexible Nasopharyngoscope in Head & Neck Cancers in Low Resource Settings - Optimization Phase
NCT04905134
Preschool Attention and Sleep Support (PASS)
NCT05862727
The Duke-Reinvestment Partners Community Collaborative (DRC)- Healthy Homes
NCT05934370
Postpartum ASA and NT-proBNP
NCT05889468
A Feasibility Trial of OCM Supplements for the Treatment of NAFLD
NCT05720702
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.