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NCT06464562 · ClinicalTrials.gov registry record · NA
LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 1
- Enrollment target
NCT06464562: Completed NA study, sponsored by Duke University.
NCT06464562 is a NA study that has completed, run by Duke University. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06464562, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 1 participants
- Enrollment target
Study Summary
Patients are living longer with metastatic lung cancer (i.e., metavivors) due to therapeutic advances, but face significant challenges. Most metavivors will ultimately die of cancer and must navigate the duality of living while dying. Unsurprisingly, metavivors endorse high psychological distress (e.g., anxiety, depression, illness non-acceptance), high symptom burden (e.g., fatigue, dyspnea, pain), and poor quality of life. Psychosocial interventions can improve outcomes, but existing paradigms are not designed to help metavivors navigate the emotional turbulence of living with metastatic disease. Dialectical Behavioral Therapy (DBT) Skills Training is an evidence-based treatment that teaches patients transdiagnostic, easy-to-use skills to both accept things as they are (mindfulness, distress tolerance) and change things within their control (emotion regulation, interpersonal effectiveness) to better navigate life challenges. However, DBT Skills Training has rarely been applied in patients with chronic illness. The investigators adapted DBT Skills Training (e.g., intervention dose, delivery, content) for patients living with metastatic lung cancer to create LiveWell, an 8-session Skills Training protocol delivered one-on-one via videoconference. Building on preliminary data and aligned with the ORBIT model for behavioral intervention development, the first phase of this study (K99, Aim 1, 1 year) aims to iteratively refine LiveWell using 1) qualitative exit interview data from a proof-of-concept study, 2) an advisory board of interested parties, 3) the Dynamic Sustainability Framework from implementation science, and 4) user testing (n= up to 10). The K99 phase will produce a standardized protocol and procedures for the second, independent phase of the study (R00) which will be registered separately. If successful, LiveWell will improve metavivor quality of life and provide a promising psychosocial intervention paradigm for other metavivors and patients with chroni
Interventions
- BEHAVIORAL LiveWell: Adapted Dialectical Behavioral Therapy Skills Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2025-02-14 |
| Est. Completion | 2025-08-06 |
| Phase | NA |
What the finished NCT06464562 record still lists
NCT06464562 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which LiveWell: Adapted Dialectical Behavioral Therapy Skills Training is the first listed.
NCT06464562 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06464562 about?
NCT06464562 is a clinical study titled "LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer". Patients are living longer with metastatic lung cancer (i.e., metavivors) due to therapeutic advances, but face significant challenges. Most metavivors will ultimately die of cancer and must navigate the duality of living while dying. Unsurprisingly, metavivors endorse high psychological distress (e...
What is the current status of trial NCT06464562?
This trial is currently completed. It is a NA study. The enrollment target is 1 participants. The study started on 2025-02-14. Estimated completion is 2025-08-06.
What interventions are being tested in trial NCT06464562?
The interventions under investigation include: LiveWell: Adapted Dialectical Behavioral Therapy Skills Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT06464562?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06464562's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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