Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 5 of 35
Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer
NCT05634720
Accelerated TMS for Focal Hand Dystonia
NCT06015672
Creating Access to Resources and Economic Support
NCT05971160
Sling vs No Sling After Reverse Total Shoulder Arthroplasty
NCT06092996
Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)
NCT05634707
Eat Well Produce Benefit for Diabetes and Food Insecurity
NCT05896644
PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung
NCT05553834
Implementation of the ACP Guideline for Low Back Pain (IMPACt-LBP)
NCT05626049
Meaning-Centered Pain Coping Skills Training for Cancer Pain
NCT05385965
COVID-19 Quick Start - Test and Treat in Africa
NCT06360783
Xenon MRI and Progressive ILD
NCT05241275
The PASTDUe Nutrition Ecosystem Project (PASTDUe)
NCT05127109
Outcomes Database to prospectivelY aSSEss the Changing TherapY Landscape in Renal Cell Carcinoma
NCT04919122
COVID-19 Vaccine Responses in PIDD Subjects
NCT05321407
MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases
NCT04246879
Onco-primary Care Networking to Support TEAM-based Care
NCT04258813
Well-Being After Breast Cancer Surgery
NCT04225585
Perioperative Evaluation of Cerebellar Tumors
NCT04463979
Navigation Study: Durham
NCT04438031
Peer Coaching Intervention in Young Adults With Congenital Heart Disease
NCT04271358
Improving Women's Function After Pelvic Radiation
NCT04544735
Genentech Xenon MRI Idiopathic Pulmonary Fibrosis
NCT04071769
The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)
NCT04207944
Duke COVID-19 Shared Data and Specimen Repository
NCT04368234
Developing a Management Approach for Patients With "Late-Onset" Pompe Disease
NCT03694561
Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma
NCT03681535
Project HOPE 1000: Health Outcomes Pregnancy Exposures
NCT04417283
FCT Study: Reducing the Need for Out-of-Home Placements
NCT03641664
PaRTNer: Patient Reported Outcomes and Financial Toxicity in Head and Neck Cancer A Pilot, Survey Based Study
NCT03506451
Hepatic Resection for Metastatic Pancreatic Cancer
NCT02892305
Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers
NCT03403465
Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immunotherapy in Genitourinary Malignancies (CTC Immune Based Biomarkers)
NCT02978118
Evaluation of Biomarkers in Human Synovial Fluid
NCT02664870
Preoperative Single-Fraction Radiotherapy in Early Stage Breast Cancer
NCT02482376
Durham Connects RCT Evaluation II
NCT01843036
Durham Connects RCT Evaluation
NCT01406184
The MURDOCK Study Registry and Biorepository Horizon 1.5
NCT01708408
University of North Carolina Alumni Heart Study
NCT00005398
Multisite Prevention of Conduct Problems (Fast Track)
NCT01653535
Vaginal Dilator Therapy After Pelvic Radiation
NCT07216456
Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress
NCT06999109
Mitigating Racial Disparities in Shared Decision Making in the Intensive Care Unit
NCT05710744
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress
NCT07634419
Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke
NCT06875206
ORASIS in Breast Reconstruction
NCT07670754
Comparing Strategies to Improve Non-Pharmacologic Pain Relief for Adults With Back Pain Using the Education, Navigated Care, and Supported Self-management Pain Care Program
NCT07679178
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
NCT07275359
The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study
NCT07216963
SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers
NCT07429292
Compact Auto-Aligning Multi-Modal Eye Imaging to Diagnose Traumatic Eye Injury
NCT07218835
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.