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NCT07567794 · ClinicalTrials.gov registry record

GBPDC: Gut-Brain in PD Consortium Master Protocol

A clinical trial, sponsored by Duke University.

Not yet
Registry status
250
Enrollment target

NCT07567794: Clinical Trial study, sponsored by Duke University.

NCT07567794 is a clinical trial that has not yet begun recruiting, run by Duke University. The registered enrollment target is 250 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07567794 has not yet begun recruiting, sponsored by Duke University.

NOT YET RECRUITING
Registry status
250 participants
Enrollment target

Study Summary

The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's disease (PD). The National Institute of Diabetes and Digestive and Kidney Diseases is sponsoring this research study. During this study, specific groups of participants, also known as "cohorts", will be identified based on the severity of their PD. There will also be a cohort enrolling participants who do not have Parkinson's and a cohort enrolling participants that are at risk for developing PD. Each of these cohorts will be compared to the others to assess the differences in the gut-brain connection. Participants in this study will: * meet with a medical provider * answer questionnaires * give samples of blood, stool, and saliva * have X-rays taken while swallowing different foods (swallowing study) * have X-rays taken to see how long it takes markers to move through their colon (colon transit study) * have a flexible sigmoidoscopy, where a doctor looks inside the lower part of the colon and takes small tissue samples (biopsies) from the mucosa (lining) * have samples taken of their skin * have an anorectal manometry and a balloon expulsion test, where a small tube and balloon are placed in the rectum to measure muscle function. Participation in the study will last up to 24 months (2 years).

Primary Outcome

Trait and State cross-sectional evaluation of GI influences on PD

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2026-06-04
Est. Completion 2028-12-31
Duke University

1,725 total trials

What is known before NCT07567794 opens enrollment

NCT07567794 is an observational study that tracks outcomes without assigning an intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT07567794 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07567794 about?

NCT07567794 is a clinical study titled "GBPDC: Gut-Brain in PD Consortium Master Protocol". The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's disease (PD). The National Institute of Diabetes and Digestive and Kidney Diseases is sponsoring this research study. During this study, speci...

What is the current status of trial NCT07567794?

This trial is currently not yet recruiting. The enrollment target is 250 participants. The study started on 2026-06-04. Estimated completion is 2028-12-31.

Who is sponsoring clinical trial NCT07567794?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT07567794, the US trial registry maintained by the National Library of Medicine. NCT07567794 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.