Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 17 of 35

TERMINATED

Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers

NCT03134027

COMPLETED Phase 2

Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED)

NCT03064490

COMPLETED

Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan

NCT03207503

COMPLETED Phase 2

Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide

NCT02991456

COMPLETED NA

Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia

NCT03218397

COMPLETED NA

Prevention of Urinary Stones With Hydration

NCT03244189

COMPLETED

MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis

NCT02845635

TERMINATED Phase 4

Rejuvenated RBC and VO2 Max in Healthy Subjects

NCT03089047

COMPLETED Phase 2

Alternative Schedule Sunitinib in Metastatic Renal Cell Carcinoma: Cardiopulmonary Exercise Testing

NCT03109015

COMPLETED NA

Mindfulness and Yoga Training for Athletes With Concussion (MYTAC)

NCT03304327

COMPLETED NA

Teaching Improved Communication To Adolescents and Clinicians

NCT03152045

COMPLETED Phase 4

Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings

NCT02978417

COMPLETED

BRS and Outcomes in Cardiothoracic Surgery

NCT03243279

TERMINATED Phase 4

Lung Transplantation in Chronic HCV Infection With Post Transplant EPCLUSA Treatment

NCT03207399

COMPLETED NA

Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension

NCT03041441

COMPLETED

The Innervation of Human Gut Sensory Epithelial Cells

NCT02888587

TERMINATED Phase 4

Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve

NCT03249272

TERMINATED Phase 4

Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU

NCT02903407

COMPLETED Phase 4

FLUAD® vs. Fluzone® High-Dose Study

NCT03183908

COMPLETED Phase 4

Effect of Bupropion on Seizure Threshold in Depressed Patients

NCT03126682

COMPLETED Phase 4

Fever After Simultaneous Versus Sequential Vaccination in Young Children

NCT03165981

COMPLETED NA

Cell Phone Application for Vision Assessment

NCT03212222

COMPLETED

Olympus - 19-gauge Needle

NCT03270670

TERMINATED NA

Prehabilitation Exercise Plus Perioperative Optimization of Senior Health

NCT03291795

COMPLETED

Stated-Preferences in Knee Arthroplasty

NCT03058380

TERMINATED NA

Perioperative Smoking Cessation Interventions

NCT03222908

COMPLETED NA

Integration of Musculoskeletal Physical Therapy Care in the Patient Centered Medical Home

NCT03110211

COMPLETED NA

Mobile Health Behavioral Intervention in Patients With Heart Failure and Diabetes Mellitus

NCT02918175

TERMINATED Phase 4

Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty

NCT02933671

COMPLETED NA

DASH Cloud: Using Digital Health to Improve Adherence to the DASH Diet Among Women

NCT03215472

TERMINATED Phase 4

Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension

NCT03044314

COMPLETED NA

Patient Performed Examination for Patients With Intra-articular Hip Pain

NCT03248934

COMPLETED

A Rapid Test for Acute Respiratory Illness

NCT03192072

TERMINATED NA

Applications of Dual Energy CT in Patients With Osseous Metastases From Castrate-resistant Prostate Cancer

NCT03111914

COMPLETED Phase 1

Study of Pembrolizumab With Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumors

NCT03043664

COMPLETED NA

Is There a Digital Divide in Chronic Kidney Disease (CKD)?

NCT03067779

TERMINATED Phase 4

Hydroxychloroquine and Cognitive Function After Surgery

NCT03025087

COMPLETED NA

Understanding the Role of Patient Behavior Change in Improving AKI Outcomes

NCT03114592

COMPLETED

OSA in Pregnant Women With Chronic HTN

NCT03230110

COMPLETED

Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults

NCT03273335

COMPLETED Phase 2

Adaptive Pharmacotherapy for Smoking Cessation

NCT02501265

COMPLETED NA

Cancer Distress Coach Mobile App Trial

NCT02986152

COMPLETED

Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines

NCT03037021

COMPLETED NA

Impact of Therapy Dog Presence on Pediatric Echocardiogram

NCT03059407

COMPLETED NA

Preventing Pressure Ulcers With Repositioning Frequency and Precipitating Factors

NCT02996331

COMPLETED Phase 1

Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness

NCT03069482

COMPLETED

Changing the Pulse of Athletics: Applying a Standardized Cardiac Athletic Screening for NCAA Athletes

NCT03150940

COMPLETED Phase 4

Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes

NCT03081052

COMPLETED

Immunologic Signatures Following Surgery for Pancreatic Cancer

NCT03001518

COMPLETED NA

Williams LifeSkills - Cancer Caregiver Intervention

NCT03174626

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.