Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 17 of 35
Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers
NCT03134027
Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED)
NCT03064490
Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan
NCT03207503
Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide
NCT02991456
Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia
NCT03218397
Prevention of Urinary Stones With Hydration
NCT03244189
MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis
NCT02845635
Rejuvenated RBC and VO2 Max in Healthy Subjects
NCT03089047
Alternative Schedule Sunitinib in Metastatic Renal Cell Carcinoma: Cardiopulmonary Exercise Testing
NCT03109015
Mindfulness and Yoga Training for Athletes With Concussion (MYTAC)
NCT03304327
Teaching Improved Communication To Adolescents and Clinicians
NCT03152045
Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings
NCT02978417
BRS and Outcomes in Cardiothoracic Surgery
NCT03243279
Lung Transplantation in Chronic HCV Infection With Post Transplant EPCLUSA Treatment
NCT03207399
Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension
NCT03041441
The Innervation of Human Gut Sensory Epithelial Cells
NCT02888587
Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
NCT03249272
Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU
NCT02903407
FLUAD® vs. Fluzone® High-Dose Study
NCT03183908
Effect of Bupropion on Seizure Threshold in Depressed Patients
NCT03126682
Fever After Simultaneous Versus Sequential Vaccination in Young Children
NCT03165981
Cell Phone Application for Vision Assessment
NCT03212222
Olympus - 19-gauge Needle
NCT03270670
Prehabilitation Exercise Plus Perioperative Optimization of Senior Health
NCT03291795
Stated-Preferences in Knee Arthroplasty
NCT03058380
Perioperative Smoking Cessation Interventions
NCT03222908
Integration of Musculoskeletal Physical Therapy Care in the Patient Centered Medical Home
NCT03110211
Mobile Health Behavioral Intervention in Patients With Heart Failure and Diabetes Mellitus
NCT02918175
Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty
NCT02933671
DASH Cloud: Using Digital Health to Improve Adherence to the DASH Diet Among Women
NCT03215472
Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension
NCT03044314
Patient Performed Examination for Patients With Intra-articular Hip Pain
NCT03248934
A Rapid Test for Acute Respiratory Illness
NCT03192072
Applications of Dual Energy CT in Patients With Osseous Metastases From Castrate-resistant Prostate Cancer
NCT03111914
Study of Pembrolizumab With Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumors
NCT03043664
Is There a Digital Divide in Chronic Kidney Disease (CKD)?
NCT03067779
Hydroxychloroquine and Cognitive Function After Surgery
NCT03025087
Understanding the Role of Patient Behavior Change in Improving AKI Outcomes
NCT03114592
OSA in Pregnant Women With Chronic HTN
NCT03230110
Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults
NCT03273335
Adaptive Pharmacotherapy for Smoking Cessation
NCT02501265
Cancer Distress Coach Mobile App Trial
NCT02986152
Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines
NCT03037021
Impact of Therapy Dog Presence on Pediatric Echocardiogram
NCT03059407
Preventing Pressure Ulcers With Repositioning Frequency and Precipitating Factors
NCT02996331
Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness
NCT03069482
Changing the Pulse of Athletics: Applying a Standardized Cardiac Athletic Screening for NCAA Athletes
NCT03150940
Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes
NCT03081052
Immunologic Signatures Following Surgery for Pancreatic Cancer
NCT03001518
Williams LifeSkills - Cancer Caregiver Intervention
NCT03174626
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.