Duke University
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Trial Pipeline
1,725 total, page 17 of 35
Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers
NCT03134027
Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED)
NCT03064490
Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan
NCT03207503
Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide
NCT02991456
Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia
NCT03218397
Prevention of Urinary Stones With Hydration
NCT03244189
MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis
NCT02845635
Rejuvenated RBC and VO2 Max in Healthy Subjects
NCT03089047
Alternative Schedule Sunitinib in Metastatic Renal Cell Carcinoma: Cardiopulmonary Exercise Testing
NCT03109015
Mindfulness and Yoga Training for Athletes With Concussion (MYTAC)
NCT03304327
Teaching Improved Communication To Adolescents and Clinicians
NCT03152045
Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings
NCT02978417
BRS and Outcomes in Cardiothoracic Surgery
NCT03243279
Lung Transplantation in Chronic HCV Infection With Post Transplant EPCLUSA Treatment
NCT03207399
Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension
NCT03041441
The Innervation of Human Gut Sensory Epithelial Cells
NCT02888587
Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
NCT03249272
Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU
NCT02903407
FLUAD® vs. Fluzone® High-Dose Study
NCT03183908
Effect of Bupropion on Seizure Threshold in Depressed Patients
NCT03126682
Fever After Simultaneous Versus Sequential Vaccination in Young Children
NCT03165981
Cell Phone Application for Vision Assessment
NCT03212222
Olympus - 19-gauge Needle
NCT03270670
Prehabilitation Exercise Plus Perioperative Optimization of Senior Health
NCT03291795
Stated-Preferences in Knee Arthroplasty
NCT03058380
Perioperative Smoking Cessation Interventions
NCT03222908
Integration of Musculoskeletal Physical Therapy Care in the Patient Centered Medical Home
NCT03110211
Mobile Health Behavioral Intervention in Patients With Heart Failure and Diabetes Mellitus
NCT02918175
Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty
NCT02933671
DASH Cloud: Using Digital Health to Improve Adherence to the DASH Diet Among Women
NCT03215472
Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension
NCT03044314
Patient Performed Examination for Patients With Intra-articular Hip Pain
NCT03248934
A Rapid Test for Acute Respiratory Illness
NCT03192072
Applications of Dual Energy CT in Patients With Osseous Metastases From Castrate-resistant Prostate Cancer
NCT03111914
Study of Pembrolizumab With Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumors
NCT03043664
Is There a Digital Divide in Chronic Kidney Disease (CKD)?
NCT03067779
Hydroxychloroquine and Cognitive Function After Surgery
NCT03025087
Understanding the Role of Patient Behavior Change in Improving AKI Outcomes
NCT03114592
OSA in Pregnant Women With Chronic HTN
NCT03230110
Investigating NeuroinflammaTion UnderlyIng Postoperative Brain Connectivity Changes, POCD, Delirium in Older Adults
NCT03273335
Adaptive Pharmacotherapy for Smoking Cessation
NCT02501265
Cancer Distress Coach Mobile App Trial
NCT02986152
Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines
NCT03037021
Impact of Therapy Dog Presence on Pediatric Echocardiogram
NCT03059407
Preventing Pressure Ulcers With Repositioning Frequency and Precipitating Factors
NCT02996331
Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness
NCT03069482
Changing the Pulse of Athletics: Applying a Standardized Cardiac Athletic Screening for NCAA Athletes
NCT03150940
Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation Outcomes
NCT03081052
Immunologic Signatures Following Surgery for Pancreatic Cancer
NCT03001518
Williams LifeSkills - Cancer Caregiver Intervention
NCT03174626
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What the Pipeline for Duke University Shows
According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.
The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.