Duke University
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).
Duke University: 1,725 sponsored US clinical trials, 187 recruiting.
Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.
Top-decile sponsor footprint
Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,725 total, page 18 of 35
Transphyseal Vs. Physeal Sparing ACL Reconstruction in Skeletally Immature Patients: Risk of Subsequent Lower Extremity Growth Deformity
NCT03081026
Synovial Fluid Analysis of Intraarticular Elbow Fracture
NCT02878941
Genomics and Epigenomics for New Insights in fEmale OAB (GENIE) Study
NCT03057158
A Pilot Dose-Response Biomarker Study of Brexpiprazole Treatment in PTSD
NCT02934932
Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure
NCT03035474
I HEAL for Breast Cancer Survivors With Diabetes
NCT02970344
GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss
NCT03254953
Studying Survivorship Care Plans in Head and Neck Cancer
NCT03106090
Analyzing Challenging Clinical Discussions in Orthopaedics
NCT03058393
Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT
NCT02870101
DPE Technique in Labor Epidural for Morbidly Obese Women
NCT03074695
Utilizing Transcranial Direct Current Stimulation to Enhance Laparoscopic Technical Skills Training
NCT03083483
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
NCT02420015
Intravenous Versus Oral Acetaminophen in Primary Total Hip Arthroplasty
NCT02839876
Improving Well-Being for Breast Cancer Patients
NCT02707471
Early Recognition and Response to Increases in Surgical Site Infections Using Optimized Statistical Process Control Charts: The Early 2RIS Study
NCT03075813
Episodic to Real-Time Care in Diabetes Self-Management
NCT03012074
EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)
NCT02816736
PrEP for HBCUs (Study 2)
NCT03080597
Project IMPACT: Improving Memory Performance by Applying Cognitive Training
NCT02909101
Novel Use of an Enhanced Fluoroscopic Imaging Device to Reduce Radiation Exposure and Operative Time During Intramedullary Nailing of Hip Fractures
NCT02856828
The Cognitive Resilience Study
NCT03016702
Delivery of Pharmacogenetic Testing in a Community Pharmacy Setting
NCT02937545
Comparison of Affect-based, Self-selected, and Traditional Exercise Prescriptions
NCT03047590
Feasibility and Smokers' Reactions to DNA Feedback
NCT02922790
Respiratory Muscle Training in L-Onset Pompe Disease (LOPD)
NCT02801539
Endometrial Cancer Diet and Exercise
NCT02987881
Characterization and Epigenetics of Post-Partum Preeclampsia
NCT02935556
Putting Patients at the Center of Kidney Care Transitions (PREPARE NOW)
NCT02722382
SIMT Stereotactic Radiosurgery Outcomes Study
NCT02886572
Levomilnacipran ER vs. Adjunctive Quetiapine for Adults With Inadequate Relief With SSRIs in MDD
NCT02720198
Psychiatric Comorbidity
NCT02927652
Palliative Care For Me (PCforMe)
NCT03874195
Communicating About Sexual Concerns and Dysfunction Effectively (CASCADE) Program
NCT03658161
Splanchnic Nerve Anesthesia in Heart Failure
NCT02669407
Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers
NCT02989038
Using a Geriatric Oncology Assessment to Link With Services
NCT02906592
Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care
NCT03003403
Novel Approaches to Reducing Tobacco Related Harm
NCT02600273
Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)
NCT02873754
Psychology of Minimally Invasive Surgical Scars
NCT03004560
Four Conversations RCT
NCT02944344
Educating Anesthesia Residents to Improve Perioperative Care for the Elderly
NCT03008863
Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions
NCT02731157
Hepatitis C Virus(HCV) Heart and Lung Study
NCT02858180
TMS Modulation of Insula-related Brain Networks.02
NCT02919423
Optimizing Delivery of a Behavioral Cancer Pain Intervention Using a SMART
NCT02791646
Characterizing HIV-related Diastolic Dysfunction
NCT02860156
Comparison of PIEB vs CEI for Labor Analgesia
NCT02949271
Combination Nicotine Patch / Lorcaserin for Smoking Cessation
NCT02906644
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 136 |
| Phase 2 | 175 |
| Phase 3 | 41 |
| Phase 4 | 134 |
Therapeutic Areas
What is open in the Duke University pipeline
187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).
Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).
Top condition: Obesity (15 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Duke University: open-pipeline peers nationwide
Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,725 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- VA Office of Research and Development · 1,668 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
Sponsors near 11% open enrollment (± trial volume)
- Carnegie Mellon University · 11% recruiting · 37 trials
- CAMC Health System · 11% recruiting · 28 trials
- UConn Health · 11% recruiting · 178 trials
- Hartford Hospital · 11% recruiting · 75 trials
Related
What to do with this Duke University page
1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.
- 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.