Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03041441 · ClinicalTrials.gov registry record · NA
Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension
A NA study, sponsored by Duke University.
- Completed
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT03041441: Completed NA study, sponsored by Duke University.
NCT03041441 is a NA study that has completed, run by Duke University. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03041441, a NA study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
The purpose of this study is to estimate the intracranial pressure (ICP, the pressure in your head) in subjects with intracranial hypotension (a condition caused by leakage of the fluid that surrounds your brain and spine) using non-invasive magnetic resonance imaging (MRI) techniques, and to determine whether changes in estimated ICP are seen after treatment of this condition.
Primary Outcome
The measurement of the momentary differences between the volumes of blood and CSF entering and leaving the cranium during the cardiac cycle provides an estimate of the intracranial volume change, and the pressure difference is estimated using the derivative of the CSF velocities.
Interventions
- PROCEDURE Lumbar puncture
- DEVICE MRI algorithm
- PROCEDURE Epidural patching
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2017-09-14 |
| Est. Completion | 2019-10-26 |
| Phase | NA |
What the finished NCT03041441 record still lists
NCT03041441 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which Lumbar puncture is the first listed.
NCT03041441 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03041441 about?
NCT03041441 is a clinical study titled "Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension". The purpose of this study is to estimate the intracranial pressure (ICP, the pressure in your head) in subjects with intracranial hypotension (a condition caused by leakage of the fluid that surrounds your brain and spine) using non-invasive magnetic resonance imaging (MRI) techniques, and to determ...
What is the current status of trial NCT03041441?
This trial is currently completed. It is a NA study. The enrollment target is 5 participants. The study started on 2017-09-14. Estimated completion is 2019-10-26.
What interventions are being tested in trial NCT03041441?
The interventions under investigation include: Lumbar puncture (PROCEDURE), MRI algorithm (DEVICE), Epidural patching (PROCEDURE).
Who is sponsoring clinical trial NCT03041441?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03041441's enrollment target sits among peer trials
5 1988th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI