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NCT03025087 · ClinicalTrials.gov registry record · Phase 4
Hydroxychloroquine and Cognitive Function After Surgery
A Phase 4 study, sponsored by Duke University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 24
- Enrollment target
NCT03025087: Clinical Trial Phase 4 study, sponsored by Duke University.
NCT03025087 is a Phase 4 study that was terminated before completion, run by Duke University. The registered enrollment target is 24 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03025087, a Phase 4 study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether hydroxychloroquine decreases the relative leakage of the brain barrier after surgery.
Primary Outcome
Ktrans represents the "permeability" or "leakage" constant across the blood-brain barrier and is calculated by measuring the amount of gadolinium-based contrast agent in the extravascular-extracellular space. Ktrans is a constant assessed on the postoperative MRI and has no units of measure.
Interventions
- DRUG Hydroxychloroquine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2017-06-19 |
| Est. Completion | 2024-04-19 |
| Phase | Phase 4 |
Why NCT03025087 stopped before completion
NCT03025087 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Hydroxychloroquine is the first listed.
NCT03025087 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03025087 about?
NCT03025087 is a clinical study titled "Hydroxychloroquine and Cognitive Function After Surgery". The purpose of this study is to determine whether hydroxychloroquine decreases the relative leakage of the brain barrier after surgery.
What is the current status of trial NCT03025087?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2017-06-19. Estimated completion is 2024-04-19.
What interventions are being tested in trial NCT03025087?
The interventions under investigation include: Hydroxychloroquine (DRUG).
Who is sponsoring clinical trial NCT03025087?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03025087's enrollment target sits among peer trials
24 1699th of 2000 higher than 276 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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