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NCT03089047 · ClinicalTrials.gov registry record · Phase 4
Rejuvenated RBC and VO2 Max in Healthy Subjects
A Phase 4 study, sponsored by Duke University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 9
- Enrollment target
NCT03089047 is a Phase 4 study that was terminated before completion, run by Duke University. The registered enrollment target is 9 participants.
The verdict
NCT03089047, a Phase 4 study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 9 participants
- Enrollment target
Study Summary
To compare the physiologic benefits of rejuvenated RBCs (rejRBCs) to standards RBCs (PRBCs), we will emulate critical conditions by safely maximizing stress on the cardiovascular system, in an elective, feasible volunteer study. Maximal oxygen uptake (VO2max) will be measured in an anemic, post-donation, pre-transfusion state, and also after transfusing 14-day-old, autologous blood randomized to standard storage or standard storage with rejuvenation. We hypothesize that transfusion of standard PRBCs is less effective at increasing oxygen delivery (measured by VO2max) compared with transfusion of rejRBCs.
Interventions
- BIOLOGICAL Transfusion of rejuvenated and washed autolgous RBCs
- BIOLOGICAL Transfusion of washed autolgous RBCs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2017-09-29 |
| Est. Completion | 2018-04-18 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03089047
The ClinicalTrials.gov registry entry for NCT03089047 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Transfusion of rejuvenated and washed autolgous RBCs is the first listed.
NCT03089047 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03089047 about?
NCT03089047 is a clinical study titled "Rejuvenated RBC and VO2 Max in Healthy Subjects". To compare the physiologic benefits of rejuvenated RBCs (rejRBCs) to standards RBCs (PRBCs), we will emulate critical conditions by safely maximizing stress on the cardiovascular system, in an elective, feasible volunteer study. Maximal oxygen uptake (VO2max) will be measured in an anemic, post-dona...
What is the current status of trial NCT03089047?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 9 participants. The study started on 2017-09-29. Estimated completion is 2018-04-18.
What interventions are being tested in trial NCT03089047?
The interventions under investigation include: Transfusion of rejuvenated and washed autolgous RBCs (BIOLOGICAL), Transfusion of washed autolgous RBCs (BIOLOGICAL).
Who is sponsoring clinical trial NCT03089047?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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