Duke University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Duke University sits in the top decile of US sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count).

1,725 total trials 187 currently recruiting 1244 completed early-phase tilt top decile by trial count

Duke University: 1,725 sponsored US clinical trials, 187 recruiting.

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Top-decile sponsor footprint

Duke University ranks in the top decile of sponsors by registered trial count (#9 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 55/100

1,244 of 1,444 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,725 total, page 16 of 35

COMPLETED NA

Gaitbox Validation Study

NCT03406806

COMPLETED

Blood Biomarker of Alzheimer's Disease (AD)

NCT03340571

COMPLETED

Respiratory Control and Narcotic Effects

NCT04047550

COMPLETED NA

Alpha MSH in Ocular Disease

NCT03451578

COMPLETED Phase 4

Effects of Smoking Environments on Brain Reactivity

NCT03421210

COMPLETED NA

Ketogenic Diet for Reduction of CNS Oxygen Toxicity in Working Divers

NCT03433261

TERMINATED NA

Self-activation in Individuals With and Without Nicotine Dependence

NCT03170258

COMPLETED NA

A Comparison of Peripheral Nerve Catheter Securement Techniques at the Insertion Site in Healthy Volunteers

NCT03375190

COMPLETED NA

Feasibility of Care Coordination

NCT04171596

COMPLETED

Risk-score Based ICU Triage

NCT03390270

COMPLETED

Stigma, Self-management, & Quality of Life in SCD

NCT03488264

COMPLETED NA

Decompression Tables for Diving at Altitude

NCT03390335

TERMINATED NA

BRIDGE Device for Post-operative Pain Control

NCT03265249

COMPLETED

Role of Social Incentives in PRO Collection

NCT03436446

COMPLETED NA

AML Electronic Decision Aid

NCT03442452

TERMINATED NA

Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD)

NCT03387033

COMPLETED NA

Very Low Birth Weight Preterm Infant Bundled Care in the NICU

NCT03370757

COMPLETED NA

Focal Breast Pain: Does a Normal Ultrasound Provide Reassurance?

NCT02810236

COMPLETED NA

Charge: A Text Messaging-based Weight Loss Intervention

NCT03254940

COMPLETED

Race-related Alternative Splicing: Novel Targets in Prostate Cancer

NCT03424213

COMPLETED NA

Effective Management of Emotional Response to Generate Well-Being Post-HF Exacerbation

NCT03043261

COMPLETED

Blood Biomarker in Early Parkinson's Disease

NCT03384797

COMPLETED Phase 4

Neurobehavioral Substrates of Propranolol's Effects on Drug Cue Reactivity

NCT03309943

TERMINATED NA

Effects of rTMS on Human Brain Activity Measured With fMRI

NCT03259568

COMPLETED Phase 2

KeyLargo: Pembrolizumab + Oxaliplatin + Capecitabine in Gastric Cancer

NCT03342937

COMPLETED NA

A Trial of an Integrated Clinic-community Intervention in Children and Adolescents With Obesity (Hearts and Parks)

NCT03339440

COMPLETED Early Phase 1

INJECT: A Pilot Study of Intra-tumoral Injections in Metastatic Urological Cancers

NCT03071328

COMPLETED Phase 2

Transforaminal Versus Lateralized Interlaminar Cervical Epidurals

NCT03389620

COMPLETED NA

Telephone-Based Mindfulness CBT for Patients in Community Settings With Advanced Cancer

NCT03285633

TERMINATED NA

Fathers Raising Responsible Men (FRRM): Addressing Sexual Health

NCT03429985

COMPLETED NA

Feasibility of VIIT in Adults With NASH

NCT03861819

COMPLETED NA

Glenohumeral Rotation After Throwing: RCT Comparing the Sleeper Stretch to the 90/90 Hip Lift With Balloon Blow Exercise

NCT03091530

COMPLETED NA

Utilizing Gaze Training to Enhance Laparoscopic Skills Training

NCT03413943

COMPLETED NA

Parent Educational Discharge Support Strategies

NCT03227068

COMPLETED NA

Study to Test the Feasibility, Acceptability, and Weight Change of Take Off Pounds Sensibly (TOPS) in a Safety Net Clinic

NCT03202420

COMPLETED Phase 2

A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment

NCT03276975

COMPLETED Phase 1

Use of ARINA-1 in an Intermediate Size Patient Population of Bilateral Lung Transplant Patients With CLAD Grade 0

NCT03226431

COMPLETED NA

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT03353246

COMPLETED Phase 2

Locally Advanced NSCLC Hyperfractionated RT

NCT03128008

COMPLETED NA

Pilot Study Assessing Breast Temperature in Breast Cancer Patients

NCT03376035

TERMINATED

Prosthetics Registry and Outcomes in Urology at Duke

NCT03323645

COMPLETED NA

Pain Coping Skills and Meaning-Centered Intervention

NCT03207360

COMPLETED

Cannabis Use and Epigenetic Alterations in Human Male Sperm Cells

NCT03614637

TERMINATED NA

Fulfillment of Expectations for Patients With FAI Syndrome

NCT03278353

COMPLETED

Pompe Gene Therapy- Screening for Eligibility

NCT03285126

TERMINATED NA

Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure

NCT03286426

COMPLETED Phase 4

Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty- Multi-center Trial

NCT03283878

COMPLETED NA

Theta Burst Stimulation for Schizophrenia

NCT03288779

COMPLETED NA

Effect of Prebiotic Fiber- Enriched (scFOS) Enteral Feeding on the Microbiome in Neurological Injury Trauma Patients (PreFEED Microbiome Trial)

NCT03153397

COMPLETED

The Treatment Preferences of Women Diagnosed With Ovarian Cancer

NCT03367260

← Previous Page 16 of 35 Next →

Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What is open in the Duke University pipeline

187 recruiting of 1,725 indexed (11% open); 1,244 completed (72%).

Phase mix: 175 late (III/IV) vs 311 early (I/II) (early-phase heavy).

Top condition: Obesity (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Duke University: open-pipeline peers nationwide

Peers matched on 1,725 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Duke UniversityUniversity of California, San FranciscoStanford UniversityVA Office of Research and DevelopmentPfizerCarnegie Mellon UniversityCAMC Health SystemUConn HealthHartford Hospital
Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Duke University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,725 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Duke University page

1,725 registered trials is a research-attention snapshot, not an endorsement of Duke University or any single study.

  • 187 of Duke University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Duke University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Duke University pipeline card: 1,725 registered trials from official public datasets.Report a data error.