Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 15 of 35

COMPLETED NA

Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD

NCT03216512

TERMINATED NA

Reach Home and Read

NCT03699592

COMPLETED NA

The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain

NCT03353272

TERMINATED Phase 4

Pain Perception During Vulvar Biopsy

NCT03654417

TERMINATED NA

Patient- and Task-specific Radiation Dose Optimization for Pediatric Abdominopelvic CT Applications

NCT03429712

COMPLETED NA

The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial

NCT03517007

COMPLETED NA

System for High-Intensity Evaluation During Radiotherapy

NCT04277650

COMPLETED NA

Neuromodulatory Treatments for Pain Management in TBI

NCT03418129

COMPLETED Phase 2

Pilot Study Evaluating the Efficacy of a Topical PDE4 Inhibitor for Morphea

NCT03351114

COMPLETED

The Learning Registry

NCT03911284

COMPLETED

Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants

NCT03640494

COMPLETED NA

Neuromodulation Therapy for Task-Specific Dystonia

NCT06422104

COMPLETED NA

Treatment of Tricuspid Valve Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation Study

NCT03775759

COMPLETED NA

Exercise Training to Promote Resilience to Chronic Lymphocytic Leukemia

NCT04950452

COMPLETED

Quality of Life of Patients With Glioblastoma (GBM) Treated With Tumor-Treating Fields

NCT03501134

TERMINATED NA

Trial Comparing PLA to HIGRT (PROVE-HCC)

NCT03402607

COMPLETED Phase 2

The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products

NCT03492463

COMPLETED NA

Earplugs and Eye Masks for Reducing Delirium

NCT03471520

COMPLETED NA

Reducing Disparities in the Quality of Advance Care Planning for Older Adults

NCT03516994

TERMINATED Phase 4

Comparison of Oral Anticoagulants for Extended VEnous Thromboembolism

NCT03196349

COMPLETED NA

Testing the Feasibility of the DASH Cloud Intervention Using Amazon Alexa

NCT03455946

COMPLETED Phase 4

Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines

NCT03530124

TERMINATED NA

Effexts OF THE Cleansweep Suction Catheter

NCT03486002

COMPLETED

Low Dose CT Distal Radius Fractures

NCT03423043

COMPLETED Phase 3

TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure

NCT03296813

COMPLETED Phase 2

A Study Osimertinib in Patients With Stage 4 Non-small Cell Lung Cancer With Uncommon EGFR Mutations

NCT03434418

COMPLETED

Study of ALS Reversals 2: Genetic Analyses

NCT03464903

COMPLETED Phase 1

Atezolizumab With Neoadjuvant Chemotherapy for Patients With Newly-Diagnosed Advanced-Stage Ovarian Cancer

NCT03394885

COMPLETED NA

Digital Symptom Tracking, Patient Engagement and Quality of Life in GI Oncology Clinic Patients

NCT03459352

COMPLETED NA

Balanced (Egg) Protein During Obesity Reduction: Differential Responses of Insulin Resistance by Race

NCT03771261

COMPLETED NA

Active Recreation Through Community-Healthcare Engagement Study

NCT03246763

COMPLETED NA

Preventing Post-Vaccination Presyncope and Syncope in Adolescents Using Simple, Clinic-based Interventions: A Pilot Study

NCT03533829

COMPLETED NA

Collaboration to Promote Early Childhood Well Being in Families Experiencing Homelessness

NCT03530137

TERMINATED Phase 1

Gene-by-Stress Interactions in Intervention Studies Significance

NCT03011645

COMPLETED Phase 3

Project Q Pilot: Smoking Cessation for Light Smokers

NCT03416621

COMPLETED NA

Early Palliative Care Intervention in Malignant Glioma

NCT03471546

COMPLETED

Disease-Modifying Treatments for Myasthenia Gravis

NCT03490539

COMPLETED Phase 4

Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.

NCT03353233

COMPLETED Phase 4

Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension

NCT03390426

COMPLETED

SER Hispano Longitudinal Study

NCT03527654

COMPLETED Phase 1

Abdominal Nerve Blockade in Chronic Heart Failure.

NCT03453151

COMPLETED NA

Human Gut Microbiota and Prebiotic Response

NCT03595306

COMPLETED

REACH Implicit Bias Training Project

NCT03415308

COMPLETED NA

Physical Activity in Men Newly Diagnosed With Prostate Cancer: A Feasibility Study

NCT03331458

COMPLETED

Contributing Factors in the Pathobiology of Airway Remodeling in Obesity

NCT03115632

COMPLETED Phase 2

Metoclopramide Versus Placebo for GJ Placement

NCT03331965

COMPLETED NA

Low Cost OCT for Point of Care

NCT03323307

COMPLETED Early Phase 1

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075

NCT03248947

COMPLETED NA

Lingual Muscle Training in Late-Onset Pompe Disease (LOPD)

NCT03255213

COMPLETED

Bilateral Brain Dynamics in Cognition and Aging

NCT03224988

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.