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NCT03490539 · ClinicalTrials.gov registry record
Disease-Modifying Treatments for Myasthenia Gravis
A clinical trial, sponsored by Duke University.
- Completed
- Registry status
- 82
- Enrollment target
NCT03490539: Completed study, sponsored by Duke University.
NCT03490539 is a clinical trial that has completed, run by Duke University. The registered enrollment target is 82 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03490539 has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- 82 participants
- Enrollment target
Study Summary
This study is designed to address the evidence gaps in a real-world setting and help patients with MG choose treatments that are best suited to them. It is a prospective, multicenter observational cohort study of comparative effectiveness of MG treatments, with a patient-centered primary outcome measure, to guide clinicians, patients and payers regarding the choice of treatment options for this chronic and serious disease. Primary: To compare the effectiveness of azathioprine (AZT) and mycophenolate mofetil (MMF). Secondary: To compare the outcomes in patients receiving an adequate dose and duration of AZT or MMF over the 2-3 year study period, vs. patients not receiving adequate doses and duration of these agents
Primary Outcome
Measures MG symptoms, physical, social and emotional functioning related to MG, with 15 items, 3 response option, 0-2 for each item, Total score range 0-30, higher scores indicating worse function
Interventions
- DRUG Mycophenolate Mofetil
- DRUG Azathioprine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2018-05-07 |
| Est. Completion | 2021-01-31 |
What the finished NCT03490539 record still lists
NCT03490539 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 82 participants, a relatively small participant target.
The record links to 0 conditions, and to 2 interventions - of which Mycophenolate Mofetil is the first listed.
NCT03490539 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03490539 about?
NCT03490539 is a clinical study titled "Disease-Modifying Treatments for Myasthenia Gravis". This study is designed to address the evidence gaps in a real-world setting and help patients with MG choose treatments that are best suited to them. It is a prospective, multicenter observational cohort study of comparative effectiveness of MG treatments, with a patient-centered primary outcome mea...
What is the current status of trial NCT03490539?
This trial is currently completed. The enrollment target is 82 participants. The study started on 2018-05-07. Estimated completion is 2021-01-31.
What interventions are being tested in trial NCT03490539?
The interventions under investigation include: Mycophenolate Mofetil (DRUG), Azathioprine (DRUG).
Who is sponsoring clinical trial NCT03490539?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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